Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/32486
Full metadata record
DC FieldValue
dc.contributor.authorJustino, Maria Cleonice A.
dc.contributor.authorBrasil, Patrícia
dc.contributor.authorAbreu, Erika
dc.contributor.authorMiranda, Yllen
dc.contributor.authorMascarenhas, Joana D'Arc P.
dc.contributor.authorGuerra, Sylvia F. S.
dc.contributor.authorLinhares, Alexandre C.
dc.date.accessioned2019-04-15T14:07:05Z
dc.date.available2019-04-15T14:07:05Z
dc.date.issued2016
dc.identifier.citationJUSTINO, Maria Cleonice A. et al. Clinical severity and rotavirus vaccination among children hospitalized for acute gastroenteritis in Belém, Northern Brazil. Journal of Tropical Pediatrics, v. 62, p. 276-281, Feb. 2016.
dc.identifier.issn0142-6338
dc.identifier.urihttps://www.arca.fiocruz.br/handle/icict/32486
dc.language.isoeng
dc.publisherOxford University Press
dc.rightsrestricted access
dc.titleClinical severity and rotavirus vaccination among children hospitalized for acute gastroenteritis in Belém, Northern Brazil
dc.typeArticle
dc.identifier.doi10.1093/tropej/fmv098
dc.description.abstractenIn March 2006, Brazil introduced the monovalent rotavirus (RV) vaccine (Rotarix™) into the public sector. This study assessed the severity of rotavirus gastroenteritis (RVGE) according to the vaccination status among hospitalized children. We identified 1023 RVGE episodes among not vaccinated (n = 252), partially vaccinated (n = 156) and fully vaccinated (n = 615) children. Very severe gastroenteritis (scored ≥ 15) was reported in 16.7, 17.9 and 13.5% of not vaccinated, partially vaccinated and fully vaccinated children, respectively. There was a trend for a shorter duration of RV diarrhoea among vaccinated children than in not vaccinated children (p = 0.07). A protective effect of vaccination was noted when mean duration of symptoms and hospital stay are analysed, comparing unvaccinated, partially vaccinated and fully vaccinated children (p < 0.05). We showed a vaccination dose effect trend, with fully vaccinated children having less-severe RVGE than not vaccinated and partially vaccinated children.
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.
dc.creator.affilliationFundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.
dc.subject.enRotavirus
dc.subject.enGastroenteritis
dc.subject.enSeverity
dc.subject.enVaccination status
dc.identifier.eissn10.1093/tropej/fmv098
Appears in Collections:INI - Artigos de Periódicos

Files in This Item:
File Description SizeFormat 
ve_Justino_Maria_etal_INI_2016.pdf155.44 kBAdobe PDF    Request a copy


FacebookTwitterDeliciousLinkedInGoogle BookmarksBibTex Format mendeley Endnote DiggMySpace

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.