Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/33032
Title: Economic burden of HIV and TB/HIV coinfection in a middle-income country: a costing analysis alongside a pragmatic clinical trial in Brazil
Authors: Siqueira-Filha, Noemia Teixeira de
Albuquerque, Maria de Fatima Militao de
Rodrigues, Laura Cunha
Legood, Rosa
Santos, Andreia Costa
Affilliation: London School of Hygiene & Tropical Medicine. Global Health and Development. London, UK.
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.
London School of Hygiene & Tropical Medicine. Global Health and Development. London, UK.
London School of Hygiene & Tropical Medicine. Global Health and Development. London, UK.
London School of Hygiene & Tropical Medicine. Global Health and Development. London, UK.
Abstract: Objective The objective of this study was to measure the costs of people living with HIV (PLHIV) as well as active tuberculosis (TB/HIV), latent tuberculosis infection (LTBI/HIV) or without TB (HIV/AIDS). Methods We analysed the costs through the entire pathway of care during the prediagnosis and treatment periods from the Brazilian public health system perspective. We applied a combination of bottom-up and top-down approaches to capture and estimate direct medical and non-medical costs. We measured the mean cost per patient per type of care (inpatient, outpatient and emergency care) and disease category (HIV/AIDS, HIV/AIDS death, TB/HIV, TB/HIV death and LTBI/HIV). Results Between March 2014 and March 2016 we recruited 239 PLHIV. During the follow-up 26 patients were diagnosed and treated for TB and 5 received chemoprophylaxis for LTBI. During the prediagnosis and treatment period, the mean total costs for HIV or AIDS and AIDS death categories were US$1558 and US$2828, respectively. The mean total costs for TB/HIV and TB/ HIV death categories were US$5289.0 and US$8281, respectively. The mean total cost for the LTBI/HIV category was US$882. Conclusions Patients with TB/HIV impose a higher economic burden on the health system than HIV/AIDS and LTBI/HIV. Patients with LTBI/HIV were the lowest cost group among all disease categories, indicating that preventive TB treatment can avoid the further costs treating active TB.
Keywords: Latent Tuberculosis
Brazil
Coinfection
Cost of Illness
Costs and Cost Analysis
HIV Infections
Health Services Research
DeCS: Adulto
Brasil / epidemiologia
Coinfecção / economia
Coinfecção / epidemiologia
Custos e Análise de Custo
Fêmea
Infecções por HIV / economia
Infecções por HIV / epidemiologia
Humanos
Renda
Tuberculose Latente / epidemiologia
Masculino
Meia idade
Adulto jovem
Issue Date: 2018
Citation: TEIXEIRA DE SIQUEIRA-FILHA, N. et al. Economic Burden of HIV and TB/HIV Coinfection in a Middle-Income Country: A Costing Analysis alongside a Pragmatic Clinical Trial in Brazil. Sexually Transmitted Infections, v. 94, n. 6, p. 463–469, 2018.
DOI: 10.1136/sextrans-2017-053277
ISSN: 1472-3263
Copyright: restricted access
Appears in Collections:PE - IAM - Artigos de Periódicos

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