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Title: Childhood and Adolescent Cancer in the State of Pernambuco, Brazil: Incidence, Geographical Distribution, and Association With Environmental Health Indicators
Authors: Bastos, Lídia N. V.
Silveira, José C.
Luna, Carlos F.
Lucena-Silva, Norma
Affilliation: Public Health Department.
Public Health Department.
Public Health Department.
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Imunologia. Recife, PE, Brasil / Pediatric Oncology Service at IMIP Hospital. Recife, PE, Brasil.
Abstract: Cases of childhood and adolescent cancer diagnosed from 2009 to 2012 in the state of Pernambuco, Brazil, were analyzed considering the patients' sex and age, the type of cancer and the municipality of living to determine the incidence, geographical distribution, and association with environmental health indicators. The spatial distribution pattern of the cancer incidence was estimated using the Global Moran's index. The association between environmental health indicators and cancer incidence was evaluated by multiple regression. From 2009 to 2012, 1261 new cases of cancer were diagnosed in patients younger than 20 years old in the state of Pernambuco. Leukemia/lymphoma were the most common type of cancer contemplating 45.28% of the cases. The average age-adjusted incidence rate was 113 cases per million with no spatial distribution pattern. The municipalities were clustered according to their degree of inequality (P=0.017), human development index (P=0.001), population growth rate (P=0.008), urbanization level (P=0.001), number of agricultural crops per capita (P=0.001), and number of industries per capita (P=0.030). However, only urbanization level was positive correlated with incidence of pediatric cancer (P=0.009) likely because in more developed cities, people are more exposed to potential oncogenic factors, such as air and water pollution and processed and ultraprocessed food. The better access to specialized health services, which increases the chances of early diagnosis, may also contributes for a higher number of cases in more developed cities.
Keywords: Childhood
Environmental health
DeCS: Adolescente
Brasil / epidemiologia
Criança, pré-escolar
Exposição Ambiental / efeitos adversos
Saúde Ambiental
Poluição Ambiental / efeitos adversos
Ingredientes Alimentares / efeitos adversos
Geografia Médica
Neoplasias / epidemiologia
Neoplasias / etiologia
Fatores de risco
Fatores Socioeconômicos
Saúde Urbana
Issue Date: 2018
Citation: BASTOS, L. N. V. et al. Childhood and Adolescent Cancer in the State of Pernambuco, Brazil: Incidence, Geographical Distribution, and Association With Environmental Health Indicators. Journal of Pediatric Hematology/Oncology, v. 40, n. 1, p. 7–14, 2018.
DOI: 10.1097/MPH.0000000000001017
ISSN: 1536-3678
Copyright: restricted access
Appears in Collections:PE - IAM - Artigos de Periódicos

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