Author | Gontijo, Celia M. F. | |
Author | Pacheco, Raquel S. | |
Author | Oréfice, Fernando | |
Author | Lasmar, Euler | |
Author | Silva, Eduardo S. | |
Author | Melo, Maria Norma | |
Access date | 2020-10-26T14:49:16Z | |
Available date | 2020-10-26T14:49:16Z | |
Document date | 2002 | |
Citation | GONTIJO, Célia M. F. et al. Concurrent Cutaneous, Visceral and Ocular Leishmaniasis Caused by Leishmania (Viannia) braziliensis in a Kidney Transplant Patient. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 87, n. 5, p. 751-753, July 2002. | pt_BR |
ISSN | 0074-0276 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/44198 | |
Language | eng | pt_BR |
Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. | pt_BR |
Rights | open access | |
Subject in Portuguese | Leishmania braziliensis | pt_BR |
Subject in Portuguese | Cutânea | pt_BR |
Subject in Portuguese | Leishmaniose visceral e ocular | pt_BR |
Subject in Portuguese | Transplante de rim | pt_BR |
Title | Concurrent Cutaneous, Visceral and Ocular Leishmaniasis Caused by Leishmania (Viannia) braziliensis in a Kidney Transplant Patient | pt_BR |
Type | Article | |
DOI | 10.1590/S0074-02762002000500029 | |
Abstract | Although cases of leishmaniasis co-infection have been described in acquired immunodeficiency syndrome patients as well as those who have undergone organ transplants, to our knowledge, the present report is the first documented case of simultaneous cutaneous, visceral and ocular leishmaniasis due to Leishmania (Viannia) braziliensis in a transplant patient. The patient had been using immunosuppressive drugs since receiving a transplanted kidney. The first clinical signs of leishmaniasis included fever, thoracic pain, hepatosplenomegaly, leucopenia and anemia. The cutaneous disease was revealed by the presence of amastigotes in the skin biopsy. After three months, the patient presented fever with conjunctive hyperemia, intense ocular pain and low visual acuity. Parasites isolated from iliac crest, aqueous humor and vitreous body were examined using a range of molecular techniques. The same strain of L. (V.) braziliensis was responsible for the different clinical manifestations. The immunosuppressive drugs probably contributed to the dissemination of Leishmania. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Leishmanioses. Belo Horizonte, MG, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade do Estado de Minas Gerais. Faculdade de Medicina. Belo Horizonte, MG, Brasil. | pt_BR |
Affilliation | Faculdade de Ciências Médicas de Minas Gerais. Belo Horizonte, MG, Brasil / Hospital Mater Dei. Belo Horizonte, MG, Brasil. | pt_BR |
Affilliation | Universidade do Estado de Minas Gerais. Fundação Educacional de Divinópolis. Divinópolis, MG Brasil. | pt_BR |
Affilliation | Universidade federal de mInas Gerais. Instituto de Ciências Biológicas. Beki Horizonte, MG, Brasil. | pt_BR |
Subject | Leishmania braziliensis | pt_BR |
Subject | Cutaneous | pt_BR |
Subject | Visceral and ocular leishmaniasis | pt_BR |
Subject | Kidney transplant | pt_BR |
e-ISSN | 1678-8060 | |