Autor(es)
Afiliação
Resumo em Inglês
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic in
southern Africa has been characterised by three distinct waves. The first was
associated with a mix of SARS-CoV-2 lineages, whilst the second and third waves were
driven by the Beta and Delta variants, respectively1–3. In November 2021, genomic
surveillance teams in South Africa and Botswana detected a new SARS-CoV-2 variant
associated with a rapid resurgence of infections in Gauteng Province, South Africa.
Within three days of the first genome being uploaded, it was designated a variant of
concern (Omicron) by the World Health Organization and, within three weeks, had
been identified in 87 countries. The Omicron variant is exceptional for carrying over
30 mutations in the spike glycoprotein, predicted to influence antibody
neutralization and spike function4. Here, we describe the genomic profile and early
transmission dynamics of Omicron, highlighting the rapid spread in regions with high
levels of population immunity.
Editor
Nature
Referência
VIANA, Raquel et al. Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa. Nature, p. 1 - 29, Jan. 2022.
DOI
10.1038/s41586-022-04411-y (2022)
ISSN
1476-4687
Notas
Autor - Múltiplas Autorias- Raquel Viana, Sikhulile Moyo, Daniel G. Amoako, Houriiyah Tegally, Cathrine Scheepers,
Christian L. Althaus, Ugochukwu J. Anyaneji, Phillip A. Bester, Maciej F. Boni,
Mohammed Chand, Wonderful T. Choga, Rachel Colquhoun, Michaela Davids,
Koen Deforche, Deelan Doolabh, Louis du Plessis, Susan Engelbrecht, Josie Everatt,
Jennifer Giandhari, Marta Giovanetti, Diana Hardie, Verity Hill, Nei-Yuan Hsiao,
Arash Iranzadeh, Arshad Ismail, Charity Joseph, Rageema Joseph, Legodile Koopile,
Sergei L. Kosakovsky Pond, Moritz U. G. Kraemer, Lesego Kuate-Lere,
Oluwakemi Laguda-Akingba, Onalethatha Lesetedi-Mafoko, Richard J. Lessells,
Shahin Lockman, Alexander G. Lucaci, Arisha Maharaj, Boitshoko Mahlangu,
Tongai Maponga, Kamela Mahlakwane, Zinhle Makatini, Gert Marais, Dorcas Maruapula,
Kereng Masupu, Mogomotsi Matshaba, Simnikiwe Mayaphi, Nokuzola Mbhele,
Mpaphi B. Mbulawa, Adriano Mendes, Koleka Mlisana, Anele Mnguni, Thabo Mohale,
Monika Moir, Kgomotso Moruisi, Mosepele Mosepele, Gerald Motsatsi,
Modisa S. Motswaledi, Thongbotho Mphoyakgosi, Nokukhanya Msomi, Peter N. Mwangi,
Yeshnee Naidoo, Noxolo Ntuli, Martin Nyaga, Lucier Olubayo, Sureshnee Pillay,
Botshelo Radibe, Yajna Ramphal, Upasana Ramphal, James E. San, Lesley Scott,
Roger Shapiro, Lavanya Singh, Pamela Smith-Lawrence, Wendy Stevens, Amy Strydom,
Kathleen Subramoney, Naume Tebeila, Derek Tshiabuila, Joseph Tsui, Stephanie van Wyk,
Steven Weaver, Constantinos K. Wibmer, Eduan Wilkinson, Nicole Wolter,
Alexander E. Zarebski, Boitumelo Zuze, Dominique Goedhals, Wolfgang Preiser,
Florette Treurnicht, Marietje Venter, Carolyn Williamson, Oliver G. Pybus, Jinal Bhiman,
Allison Glass, Darren P. Martin, Andrew Rambaut, Simani Gaseitsiwe, Anne von Gottberg & Tulio de Oliveira. Afiliaçao - Múltiplas autorias. Autor Fiocruz - Marta Giovanetti. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ, Brasil / Universidade Federal de Minas Gerais. Laboratório de Genética Celular e Molecular. Belo Horizonte, MG, Brasil.
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