Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/5957
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dc.contributor.authorDias, João Carlos Pinto
dc.contributor.authorSchofield, Christopher John
dc.contributor.authorMachado, Evandro Marques de Menezes
dc.contributor.authorFernandes, Alexandre José
dc.date.accessioned2012-12-11T16:19:47Z
dc.date.available2012-12-11T16:19:47Z
dc.date.issued2005
dc.identifier.citationDIAS, João Carlos Pinto et al. Ticks, ivermectin, and experimental Chagas disease. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, n. 8, p. 829-832, Dec. 2005.
dc.identifier.issn0037-8682
dc.identifier.urihttps://www.arca.fiocruz.br/handle/icict/5957
dc.language.isoeng
dc.rightsopen access
dc.titleTicks, ivermectin, and experimental Chagas disease
dc.typeArticle
dc.description.abstractenFollowing an infestation of dogticks in kennels housing dogs used for long-term studies of the pathogenesis of Chagas disease, we examined the effect of ivermectin treatment on the dogs, ticks, trypanosome parasites, and also on triatomine vectors of Chagas disease. Ivermectin treatment was highly effective in eliminating the ticks, but showed no apparent effect on the dogs nor on their trypanosome infection. Triatominae fed on the dogs soon after ivermectin treatment showed high mortality, but this effect quickly declined for bugs fed at successive intervals after treatment. In conclusion, although ivermectin treatment may have a transient effect on peridomestic populations of Triatominae, it is not the treatment of choice for this situation. The study also showed that although the dogticks could become infected with Trypanosoma cruzi, this only occurred when feeding on dogs in the acute phase of infection, and there was no evidence of subsequent parasite development in the ticks.
dc.creator.affilliationFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil / Fundação Oswaldo Cruz. Posto Avançado Emmanuel Dias. Bambui, MG, Brasil.
dc.creator.affilliationLondon School of Hygiene and Tropical Medicine. Pathogen Molecular Biology Unit, London, UK.
dc.creator.affilliationFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil / Fundação Oswaldo Cruz. Posto Avançado Emmanuel Dias. Bambui, MG, Brasil.
dc.creator.affilliationFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil / Fundação Oswaldo Cruz. Posto Avançado Emmanuel Dias. Bambui, MG, Brasil.
dc.subject.enChagas disease
dc.subject.enTrypanosoma cruzi
dc.subject.enRhipicephalus sanguineus
dc.subject.enivermectin
dc.subject.enTriatominae
Appears in Collections:MG - IRR - Artigos de Periódicos

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