Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/6200
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dc.contributor.authorProietti, Anna Barbara de Freitas Carneiro
dc.contributor.authorSoares, Bernadette C. Catalan
dc.contributor.authorCosta, Carlos Maurício de Castro
dc.contributor.authorMurphy, Edward L
dc.contributor.authorSabino, Ester Cerdeira
dc.contributor.authorHisada, Michie
dc.contributor.authorCastro Filho, Bernardo Galvão
dc.contributor.authorAlcantara, Luiz Carlos Júnior
dc.contributor.authorRemondegui, Carlo
dc.contributor.authorVerdonck, Kristien
dc.contributor.authorProietti, Fernando Augusto
dc.date.accessioned2013-01-15T19:13:29Z
dc.date.available2013-01-15T19:13:29Z
dc.date.issued2006
dc.identifier.citationCARNEIRO-PROIETTI, A. B. F. et al. HTLV in the Americas: challenges and perspectives. Revista Panamericana de Salud Pública, v. 19, n. 1, p. 44-53, ene. 2006.
dc.identifier.issn1020-4989
dc.identifier.urihttps://www.arca.fiocruz.br/handle/icict/6200
dc.language.isoeng
dc.rightsopen access
dc.titleHTLV in the Americas: challenges and perspectives
dc.typeArticle
dc.description.abstractenThe first description of the human T-lymphotropic virus type 1 (HTLV-1) was made in 1980, followed closely by the discovery of HTLV-2, in 1982. Since then, the main characteristics of these viruses, commonly referred to as HTLV-1/2, have been thoroughly studied. Central and South America and the Caribbean are areas of high prevalence of HTLV-1 and HTVL-2 and have clusters of infected people. The major modes of transmission have been through sexual contact, blood, and mother to child via breast-feeding. HTLV-1 is associated with adult T-cell leukemia/lymphoma (ATL), HTLV-associated myelopathy/tropical spastic paraparesis (HAM/ TSP), and HTLV-associated uveitis as well as infectious dermatitis of children. More clarification is needed in the possible role of HTLV in rheumatologic, psychiatric, and infectious diseases. Since cures for ATL and HAM/TSP are lacking and no vaccine is available to prevent HTLV-1 and HTLV-2 transmission, these illnesses impose enormous social and financial costs on infected individuals, their families, and health care systems. For this reason, public health interventions aimed at counseling and educating high-risk individuals and populations are of vital importance. In the Americas this is especially important in the areas of high prevalence.
dc.description.abstractesLa primera descripción del virus de la leucemia humana de células T tipo 1 (VLHT-1) se hizo en 1980, y al poco tiempo, en 1982, se descubrió el VLHT-2. Desde entonces las características principales de estos virus, a los que a menudo se les llama VLHT-1/2, se han estudiado exhaustivamente. Centroamérica, América del Sur y el Caribe son áreas con una alta prevalencia de VLHT-1 y VLHT-2 donde hay conglomerados de personas infectadas. Las principales vías de transmisión han sido el contacto sexual, la sangre y sus derivados, y la de madre a hijo por la leche materna. El VLHT-1 se asocia con la leucemia o el linfoma de células T maduras (LTM), la mielopatía o paraparesia tropical espástica ligada al VLHT (M/PTE), y la uveítis ligada al VLHT, así como con la dermatitis infecciosa de la infancia. Se necesita más información acerca del posible papel que desempeña el VLHT en la aparición de enfermedades reumáticas, psiquiátricas e infecciosas. En vista de que no se dispone de ninguna cura para la LTM ni la M/PTE, como tampoco de ninguna vacuna para prevenir la transmisión del VLHT-1 y VLHT-2, estas enfermedades acarrean enormes costos sociales y económicos para las personas infectadas, sus parientes y los sistemas de salud. Por este motivo, las intervenciones sanitarias orientadas a asesorar e instruir a personas y poblaciones en alto riesgo revisten una importancia crítica. En el continente americano esto cobra aun más importancia en zonas de alta prevalencia.
dc.creator.affilliationFundação Hemominas. Belo Horizonte, Minas Gerais, Brasil
dc.creator.affilliationFundação Hemominas. Belo Horizonte, Minas Gerais, Brasil
dc.creator.affilliationUniversidade Federal do Ceará. Fortaleza, Ceará, Brasil
dc.creator.affilliationUniversity of California. San Francisco, San Francisco California, United States of America
dc.creator.affilliationFundação Pró-Sangue. Hemocentro de São Paulo. São Paulo, São Paulo, Brasil
dc.creator.affilliationNational Institutes of Health. National Cancer Institute. Division of Cancer Epidemiology and Genetics, Viral Epidemiology Branch. Bethesda, Maryland, United States of America
dc.creator.affilliationFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, Brasil /
dc.subject.enHuman T-lymphotropic virus 1
dc.subject.enHuman T-lymphotropic virus 2
dc.subject.enRetroviridae
dc.subject.enRNA tumor viruses
dc.subject.enBlood donors
dc.subject.enPreventive medicine
dc.subject.enAmericas
dc.subject.decsInfecções por Deltaretrovirus/epidemiologia
dc.subject.decsDoadores de Sangue
dc.subject.decsAleitamento Materno
dc.subject.decsRegião do Caribe/epidemiologia
dc.subject.decsAmérica Central/epidemiologia
dc.subject.decsEstudos Transversais
dc.subject.decsInfecções por Deltaretrovirus/prevenção & controle
dc.subject.decsInfecções por Deltaretrovirus/transmissão
dc.subject.decsInfecções por HTLV-I/epidemiologia
dc.subject.decsInfecções por HTLV-I/prevenção & controle
dc.subject.decsInfecções por HTLV-I/transmissão
dc.subject.decsInfecções por HTLV-II/epidemiologia
dc.subject.decsInfecções por HTLV-II/prevenção & controle
dc.subject.decsInfecções por HTLV-II/transmissão
dc.subject.decsLeucemia de Células T/epidemiologia
dc.subject.decsLeucemia-Linfoma de Células T do Adulto/epidemiologia
dc.subject.decsLinfoma de Células T
dc.subject.decsParaparesia Espástica Tropical/epidemiologia
dc.subject.decsComplicações Infecciosas na Gravidez/epidemiologia
dc.subject.decsFatores de Risco
dc.subject.decsAmérica do Sul/epidemiologia
dc.subject.decsEstados Unidos/epidemiologia
dc.subject.decsAdulto
dc.subject.decsCriança
dc.subject.decsFeminino
dc.subject.decsHumanos
dc.subject.decsRecém-Nascido
dc.subject.decsMasculino
dc.subject.decsMeia-Idade
dc.subject.decsGravidez
dc.subject.decsRevisão
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