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ON THE INTERCORRELATION OF SOME FREQUENCY AND AMPLITUDE PARAMETERS OF THE HUMAN EEG AND ITS FUNCTIONAL SIGNIFICANCE. COMMUNICATION II: NEURODYNAMIC IMBALANCE IN ENDOGENOUS ASTHENIC-LIKE DISORDERS
Factor Analysis
Schizotypal Disorders
Schizophrenia
Cyclothymia
Asthenic Disorders
Depression
Attention Disorders
Mental Selectivity
Lazarev, Vladimir V. | Date Issued:
1998
Author
Affilliation
Fundação Oswaldo Cruz. Instituto Fernandes Figueira. Laboratório de Neurofisiologia Clínica. Rio de Janeiro, RJ, Brasil / National Mental Health Research Centre of the Russian Academy of Medical Sciences. Laboratory of Neurophysiology. Moscow, Russia
Abstract
In 67 borderline psychiatric patients suffering from schizotypalrslowly developing schizophrenic disorders and 18
patients suffering from cyclothymia, the factor structure of the period interval-amplitude. parameters of the EEG
proved to be similar to that obtained in normal subjects during mental activity and reported in part I Lazarev, Int. J.
Psychophysiol., 28 1998. 77]98.. However, 51 patients with schizotypal disorders with a predominance of asthenic-like
symptomatology, characterized by mild thought disorders with difficulty in focusing attention, were distinguished
from normal subjects, cyclothymic patients and other patients of schizotypy without well-defined asthenic symptoms
by significantly increased values of EEG Factor II which was positively related to the index-presence in epoch,
frequency and regularity of low-amplitude beta-waves, and reduced values of an EEG Factor III which was positively
correlated with mean alpha-period and theta-index. According to normative data part I; Lazarev, Int. J. Psychophys-
iol., 28 1998. 77]98., this probably reflects a neurodynamic imbalance between an excess of ‘cortical excitation’
Factor II. and a deficit of ‘active selective inhibition’ Factor III.. This imbalance appears to be opposite to the
changes in values of these factors found in normal subjects during focusing attention and motor automation, when
compared with relaxed wakefulness. The functional properties of Factors II and III ascribed on the basis of
psychological testing suggest that such an imbalance could reflect a predominance of successively organised
associative mental processes over the selective inhibition of irrelevant associations. This could cause difficulties in
voluntary attention, mental automation and in the performance of simultaneous mental operations. In most cases, there was no difference in Factor I which was positively related to the index, amplitude and regularity of
alpha-activity and wave amplitudes in other bands, and negatively related to the indices and mean periods of deltaand
theta-waves, the factor presumed to depict ‘general activation’. Q 1998 Elsevier Science B.V. All rights
reserved.
Keywords
EEG Period AnalysisFactor Analysis
Schizotypal Disorders
Schizophrenia
Cyclothymia
Asthenic Disorders
Depression
Attention Disorders
Mental Selectivity
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