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PreprintCopyright
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Embargo date
2060-12-31
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- MG - IRR - Preprint [62]
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SEROPREVALENCE OF ANTI-SARS-COV-2 ANTIBODIES IN CATS AND DOGS OF BELO HORIZONTE, MINAS GERAIS, BRASIL
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Abstract
SARS-CoV-2 is a zoonotic virus that can infect a wide range of animals, including cats and dogs. In the light of the high density of cats and dogs living in Brazilian urban spaces associated with the emergence of new viral variants, we developed two in-house Enzyme-linked immunosorbent assays (ELISAs) to use in serosurveillance studies. It was observed an overall seroprevalence of 16.88% and 5% in cats and dogs, respectively. A higher occurrence of seropositive animals was detected by ELISA-RBD compared to ELISA-N. The use of N-terminal domain of N may have led to serological specificity to the assay. There was no statistical difference in the occurrence of SARS-CoV-2 seropositivity between the three different groups of animals, age or sex. No significant association between FIV/FeLV and SARS-CoV-2 was detected in cats. These results provide new information about seroepidemiology of companion animals in Brazil during the COVID-19 pandemic period.
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