Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/7546
Title: Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis.
Authors: McBride, Alan John Alexander
Pereira, Fernanda Albuquerque
Silva, Emilson Domingos da
Matos, Rosan B. de
Silva, Edimilson Domingos da
Ferreira, Antonio Gomes Pinto
Reis, Mitermayer Galvão dos
Ko, Albert Icksang
Affilliation: Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Bio-Manguinhos. Rio de Janeiro, RJ, Brasil
Fundação Oswaldo Cruz. Bio-Manguinhos. Rio de Janeiro, RJ, Brasil
Fundação Oswaldo Cruz. Bio-Manguinhos. Rio de Janeiro, RJ, Brasil
Fundação Oswaldo Cruz. Bio-Manguinhos. Rio de Janeiro, RJ, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Division of International Medicine and Infectious Disease. Weill Medical College of Cornell University. New York, USA
Abstract: Access to low-cost, effective diagnosis for leptospirosis is urgently needed in developing countries. The EIE-IgM-Leptospirose, a kit produced for public health laboratories in Brazil, was shown to have a sensitivity of 76% (77 of 102 patients) and 100% (102 of 102 patients) during acute and convalescent-phase leptospirosis, respectively, and a specificity of 93-100% (total healthy and patient control subjects evaluated, 486). These findings indicate that the assay will be useful for diagnosis of this emerging infectious disease in Brazil and other developing countries.
Keywords: IgM ELISA
Diagnosis
Epidemics
Urban
serovar
Leptospira
Copenhageni
Brazil
DeCS: Ensaio de Imunoadsorção Enzimática
Imunoglobulina M/análise
Leptospirose/diagnóstico
Leptospirose/imunologia
Kit de Reagentes para Diagnóstico
Brasil/epidemiologia
Humanos
Leptospirose/epidemiologia
Sensibilidade e Especificidade
Testes Sorológicos
Issue Date: 2007
Publisher: National Institute of Health
Citation: McBRIDE, A. j. A. et al. Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis. Acta Tropica, v. 102, n. 3, p. 206-211, 2007.
ISSN: 0001-706X
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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