Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/7572
Title: Lower hookworm incidence, prevalence, and intensity of infection in children with a Bacillus Calmette-Guérin vaccination scar
Authors: Barreto, Maurício Lima
Rodrigues, Laura Cunha
Silva, R. C.
Oliveira, Ana Marlucia de
Reis, Mitermayer Galvão dos
Santos, C. A.
Blanton, Ronald Edward
Affilliation: Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil.
London School of Hygiene and Tropical Medicine. London University. London, United Kingdom.
Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil.
Universidade Federal da Bahia. School of Nutrition. Salvador, BA, Brasil.
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil.
Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil.
Division of Geographic Medicine. Case Western Reserve University. Cleveland, Ohio.
Abstract: Bacillus Calmette-Gue´rin (BCG), the most common vaccine worldwide, has broad effects on the immune system. Hookworm infections are a major source of morbidity. In response to a preliminary report of BCG vaccination protection against nematodes in human immunodeficiency virus–infected adults, data from an ongoing prospective study were analyzed to determine the intensity (eggs per gram of stool), prevalence, and incidence of different helminths in children with and without a BCG vaccination scar. Adjusted prevalence and incidence ratios were estimated by using logistic regression. Children with a BCG vaccination scar were found to have statistically significantly lower hookwormprevalence (41%), incidence (37%), and mean egg counts (39%), after controlling for age, sex, and socioeconomic factors. There was no BCG association with incidence, prevalence, or intensity of infection with Schistosoma mansoni, Ascaris lumbricoides, or Trichuris trichiura. Such protection would have implications for public health and for research on mechanisms behind human immunological responses to hookworm.
DeCS: Vacina BCG
Infecções por Uncinaria/epidemiologia
Enteropatias Parasitárias/epidemiologia
Adolescente
Animais
Ascaris lumbricoides/isolamento & purificação
Brasil/epidemiologia
Criança
Fezes/parasitologia
Seguimentos
Infecções por Uncinaria/parasitologia
Humanos
Incidência
Enteropatias Parasitárias/parasitologia
Contagem de Ovos de Parasitas
Prevalência
Schistosoma mansoni/isolamento & purificação
Trichuris/isolamento & purificação
Vacinação
Issue Date: 2000
Publisher: Infectious Diseases Society of America
Citation: BARRETO, M. L. et al. Lower hookworm incidence, prevalence, and intensity of infection in children with a Bacillus Calmette-Guérin vaccination scar. Journal of Infectious Disease, v. 182, n. 6, p. 1800-1803, 2000.
ISSN: 0022-1899
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

Files in This Item:
File Description SizeFormat 
Barreto ML Lower hookworm incidence....pdf63.69 kBAdobe PDFThumbnail
View/Open


FacebookTwitterDeliciousLinkedInGoogle BookmarksBibTex Format mendeley Endnote DiggMySpace

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.