Author | Gomes, Regis Bernardo Brandim | |
Author | Mendonça, Ivete Lopes de | |
Author | Silva, Vladimir Costa | |
Author | Ruas, Jerônimo Lopes | |
Author | Silva, Mauro Roberto Biá da | |
Author | Cruz, Maria do Socorro Pires | |
Author | Barral, Aldina Maria Prado | |
Author | Costa, Carlos Henrique Nery | |
Access date | 2014-11-21T12:27:22Z | |
Available date | 2014-11-21T12:27:22Z | |
Document date | 2007 | |
Citation | GOMES, R. B. B. et al. Antibodies against Lutzomyia longipalpis saliva in the fox Cerdocyon thous and the sylvatic cycle of Leishmania chagasi. Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 101, n. 2, p. 127-133, 2007. | pt_BR |
ISSN | 0035-9203 | |
URI | https://www.arca.fiocruz.br/handle/icict/8929 | |
Language | eng | pt_BR |
Publisher | Elsevier Ltd | pt_BR |
Rights | open access | pt_BR |
Title | Antibodies against Lutzomyia longipalpis saliva in the fox Cerdocyon thous and the sylvatic cycle of Leishmania chagasi | pt_BR |
Type | Article | pt_BR |
DOI | 10.1016/j.trstmh.2006.06.002 | |
Abstract | Sera of 11 wild Cerdocyon thous foxes from an endemic area for American visceral
leishmaniasis were tested for the presence of antibodies against salivary gland homogenates
(SGH) of Lutzomyia longipalpis. All foxes had higher levels of anti-Lu. longipalpis SGH antibodies
than foxes from non-endemic areas, suggesting contact between foxes and the vector of visceral
leishmaniasis. Sera of humans and dogs living in the same area were also tested for reactivity
against Lu. longipalpis SGHs and had a lower proportion of reactivity than foxes. Antibodies
against Leishmania chagasi were not detected in any of the foxes, but three foxes showed the
presence of parasites in the bone marrow by direct examination, PCR or by infecting the vector.
Both humans and dogs had higher levels of anti-Le. chagasi IgG antibodies than C. thous. The
finding of an antibody response against saliva of Lu. longipalpis among C. thous together with
the broad distribution of the vector in resting areas of infected foxes suggests that the natural
foci of transmission of Le. chagasi exists independently of the transmission among dogs and humans. | pt_BR |
Affilliation | Universidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório de Imunoparasitologia. Salvador, BA, Brasil | pt_BR |
Affilliation | Universidade Federal do Piauí. Laboratório de Sanidade Animal. LASAN. Teresina, PI, Brasil | pt_BR |
Affilliation | Universidade Federal do Piauí. Instituto de Doenças Tropicais Natan Portella. Laboratório de Leishmanioses. Teresina, PI, Brasil | pt_BR |
Affilliation | Universidade Federal de Pelotas. Faculdade de Veterinária. Pelotas, RS, Brasil | pt_BR |
Affilliation | Universidade Federal do Piauí. Instituto de Doenças Tropicais Natan Portella. Laboratório de Leishmanioses. Teresina, PI, Brasil | pt_BR |
Affilliation | Universidade Federal do Piauí. Instituto de Doenças Tropicais Natan Portella. Laboratório de Leishmanioses. Teresina, PI, Brasil | pt_BR |
Affilliation | Universidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório de Imunoparasitologia. Salvador, BA, Brasil | pt_BR |
Affilliation | Universidade Federal do Piauí. Instituto de Doenças Tropicais Natan Portella. Laboratório de Leishmanioses. Teresina, PI, Brasil | pt_BR |
Subject | Leishmania chagasi | pt_BR |
Subject | Lutzomyia longipalpis | pt_BR |
Subject | Cerdocyon thous | pt_BR |
Subject | Antibody | pt_BR |
Subject | Saliva | pt_BR |
Subject | Brasil | pt_BR |
DeCS | Anticorpos Antiprotozoários/sangue | pt_BR |
DeCS | Raposas/parasitologia | pt_BR |
DeCS | Leishmania infantum/imunologia | pt_BR |
DeCS | Psychodidae/imunologia | pt_BR |
DeCS | Saliva/parasitologia | pt_BR |
DeCS | Animais | pt_BR |
DeCS | Western Blotting | pt_BR |
DeCS | Medula Óssea/parasitologia | pt_BR |
DeCS | Cães | pt_BR |
DeCS | Ensaio de Imunoadsorção Enzimática | pt_BR |
DeCS | Humanos | pt_BR |
DeCS | Imunidade Celular | pt_BR |
DeCS | Camundongos | pt_BR |
DeCS | Reação em Cadeia da Polimerase/métodos | pt_BR |
DeCS | Saliva/imunologia | pt_BR |
DeCS | Glândulas Salivares/parasitologia | pt_BR |