Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/9297
Title: Epidemiological and clinical patterns of 92 patients co-infected with HIV and Mycobacterium leprae from Rio de Janeiro State, Brazil
Authors: Menezes, Vinicius M.
Nery, José Augusto C.
Sales, Anna M.
Miranda, Alice
Galhardo, Maria Clara G.
Bastos, Francisco Inácio Pinkusfeld Monteiro
Sarno, Euzenir N.
Hacker, Mariana A.
Affilliation: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto de Comunicação e Informação Científica e Tecnológica em Saúde. Rio de Janeiro, RJ, Brasil / CAPES Visiting researcher. Imperial College. London, UK.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
Abstract: Background: Many articles have shown that HIV infection can modify the clinical course of leprosy, but very scant epidemiological and clinical data about this co-infection are available in the peer-reviewed literature. Methods: We herein describe the geographical distribution and demographic characteristics of 92 HIV/Mycobacterium leprae co-infected patients assisted in a Brazilian Leprosy referral center. A multivariate analysis was performed in order to establish clinical factors associated with type 1 reaction. Results: Co-infected patient admissions have steadily increased over the last years at this referral center. Most patients were men, with a mean age of 32.3 years and presenting with the paucibacillary form of leprosy. The use of antiretroviral therapy (ART) was the only factor associated with type 1 reaction. Most patients were living in the metropolitan area and the north sub area of Rio de Janeiro City. Conclusion: Co-infected patients receiving ART have a greater chance to develop type 1 reaction. Patients living with both HIV and leprosy are likely to live in regions characterized by a high density impoverished population.
Keywords: Brazil
Leprosy and HIV co-infection
Social geography of leprosy
Type 1 reaction
Issue Date: 2014
Citation: MENEZES, V. M. et al. Epidemiological and clinical patterns of 92 patients co-infected with hiv and mycobacterium leprae from Rio de Janeiro State, Brazil. Transactions of the Royal Society of Tropical Medicine and Hygiene, v.108, n.2, p. 63-70,2014.
DOI: DOI:10.1093/trstmh/trt113
ISSN: 00359203
Copyright: open access
Appears in Collections:INI - Artigos de Periódicos
ICICT - Artigos de Periódicos
IOC - Artigos de Periódicos

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