| Author | Lambertucci, José Roberto | |
| Author | Fidelis, Thiago André | |
| Author | Pereira, Thiago Almeida | |
| Author | Coelho, Paulo Marcos Zech | |
| Author | Pereira, Neusa Araújo | |
| Author | Souza, Márcia Maria de | |
| Author | Brasileiro Filho, Geraldo | |
| Author | Pereira, Fausto Edmundo Lima | |
| Author | Antunes, Carlos Mauricio | |
| Access date | 2015-02-02T18:30:15Z | |
| Available date | 2015-02-02T18:30:15Z | |
| Document date | 2014 | |
| Citation | LAMBERTUCCI, José Roberto et al. Brain schistosomiasis in mice experimentally infected with Schistosoma mansoni. Rev. Soc. Bras. Med. Trop., Uberaba, v. 47, n. 2, 2014 . | pt_BR |
| ISSN | 0037-8682 | |
| URI | https://www.arca.fiocruz.br/handle/icict/9412 | |
| Language | eng | pt_BR |
| Publisher | Sociedade Brasileira de Medicina Tropical | pt_BR |
| Rights | open access | pt_BR |
| Title | Brain schistosomiasis in mice experimentally infected with Schistosoma mansoni | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1590/0037-8682-0083-2013 | |
| Abstract | Introduction: Human neuroschistosomiasis has been reported in the literature, but the possibility of modeling neuroschistosomiasis in mice is controversial.
Methods: In two research laboratories in Brazil that maintain the Schistosoma mansoni life cycle in rodents, two mice developed signs of brain disease (hemiplegia and spinning), and both were autopsied.
Results: S. mansoni eggs, both with and without granuloma formation, were observed in the brain and meninges of both mice by optical microscopy.
Conclusions: This is the first description of eggs in the brains of symptomatic mice that were experimentally infected with S. mansoni. An investigation of experimental neuroschistosomiasis is now feasible. | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Faculdade de Medicina. Departamento de Clínica Médica. Belo Horizonte, MG, Brasil | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Faculdade de Medicina. Departamento de Clínica Médica. Belo Horizonte, MG, Brasil | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Faculdade de Medicina. Departamento de Anatomia Patológica. Belo Horizonte, MG/Duke University Medical Center. Durham, North Carolin, USA | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil | pt_BR |
| Affilliation | Duke University Medical Center. Durham, North Carolin, USA | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Faculdade de Medicina. Departamento de Anatomia Patológica. Belo Horizonte, MG | pt_BR |
| Affilliation | Universidade Federal do Espírito Santo. Núcleo de Doenças Infecciosas. Vitória, ES, Brasil | pt_BR |
| Affilliation | Santa Casa de Misericórdia de Belo Horizonte. Belo Horizonte, MG, Brasil | pt_BR |
| Subject | Schistosomiasis | pt_BR |
| Subject | Experimental neuroschistosomiasis | pt_BR |
| Subject | Brain schistosomiasis | pt_BR |
