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Issue DateTitleAuthor(s)CopyrightType
2015Different Therapeutic Outcomes of Benznidazole and VNI Treatments in Different Genders in Mouse Experimental Models of Trypanosoma cruzi InfectionSilva, F. H. Guedes da; Batista, D. G. J.; Silva, C. F. da; Meuser, M. B.; Silva, M. R. Simões; Araújo, J. S. de; Ferreira, C. G.; Moreira, O. C.; Britto, C.; Lepesheva, G. I.; Soeiro, Maria de Nazaré C.open accessArticle
2013Clinical Follow-Up of Responses to Treatment with Benznidazol in Amazon: A Cohort Study of Acute Chagas DiseasePinto, Ana Yecê das Neves; Valente, Vera da Costa; Coura, José Rodrigues; Valente, Sebastião Aldo da Silva; Junqueira, Ana Cristina Veríssimo; Santos, Laura Cristina; Ferreira Jr., Alberto Gomes; Macedo, Roberto Cavalleiro deopen accessArticle
2016Clinical Candidate VT-1161's Antiparasitic Effect In Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme CYP51 from Trypanosoma cruziHoekstra, William J.; Hargrove, Tatiana Y.; Wawrzak, Zdzislaw; Batista, Denise da Gama Jaen; Silva, Cristiane F. da; Nefertiti, Aline S. G.; Rachakonda, Girish; Schotzinger, Robert J.; Villalta, Fernando; Soeiro, Maria de Nazaré C.; Lepesheva, Galina I.open accessArticle
2016In Vitro and In Vivo Trypanosomicidal Action of Novel Arylimidamides against Trypanosoma cruziSilva, F. H. Guedes da; Batista, D. G. J.; Meuser, M. B.; Demarque, K. C.; Fulco, T. O.; Araújo, J. S.; Silva, P. B. da; Silva, C. F. da; Patrick, D. A.; Bakunova, S. M.; Bakunov, S. A.; Tidwell, R. R.; Oliveira, G. M.; Britto, C.; Moreira, O. C.; Soeiro, M. N. C.open accessArticle
2014Towards a Paradigm Shift in the Treatment of Chronic Chagas DiseaseViotti, R.; Noya, B. Alarcón; Jorge, T. Araujo; Grijalva, M. J.; Guhl, F.; López, M. C.; Ramsey, J. M.; Ribeiro, I.; Schijan, A. G.; Sosa-Estani, S.; Torrico, F.; Gascon, J.open accessArticle
20174-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infectionCalvet, Claudia Magalhaes; Choi, Jun Yong; Thomas, Diane; Suzuki, Brian; Hirata, Ken; Lostracco-Johnson, Sharon; Mesquita, Liliane Batista de; Nogueira, Alanderson; Batista, Marcelo Meuser; Silva, Tatiana Araujo; Siqueira Neto, Jair Lage; Roush, William R.; Pereira, Mirian Claudia de Souza; McKerrow, James H.; Podust, Larissa M.open accessArticle
2012In vitro and in vivo evaluation anti-Trypanosoma cruzi activity of N-acylhydrazones oxadiazolesMeira, Cássio Santana; Guimarães, Elisalva Teixeira; Bastos, Tanira Matutino; Castro, Murilo Fagundes de; Moreira, Diogo Rodrigo de Magalhães; Santos Filho, J. M. dos; Soares, Milena Botelho Pereiraopen accessPapers presented at events
2017Mutagenic and Cytotoxicity LQB 123 Profile: Safety and Tripanocidal Effect of a Phenyl-t-Butylnitrone DerivativeCupello, Mauricio Peixoto; Saraiva, Francis Monique; Ippolito, Pedro; Fernandes, Andréia da Silva; Menna-Barreto, Rubem Figueiredo Sadok; Costa, Debora de Sousa dos Santos; Paula, Jessica Isis Oliveira; Costa, Paulo Roberto Ribeiro; Nogueira, Natália Pereira; Felzenswalb, Israel; Dias, Ayres Guimarães; Paes, Marcia Cristinaopen accessArticle
2010Structural modelling and comparative analysis of homologous, analogous and specific proteins from Trypanosoma cruzi versus Homo sapiens: putative drug targets for chagas’ disease treatmentCapriles, Priscila V. S. Z.; Guimarães, Ana C. R.; Otto, Thomas D.; Miranda, Antonio B.; Dardenne, Laurent E.; Degrave, Wim M.open accessArticle
2017Therapeutic effects of sphingosine kinase inhibitor N,N-dimethylsphingosine (DMS) in experimental chronic Chagas disease cardiomyopathyVasconcelos, Juliana Fraga; Meira, Cássio Santana; Silva, Daniela Nascimento; Nonaka, Carolina Kymie Vasques; Daltro, Pâmela Santana; Macambira, Simone Garcia; Domizi, Pablo Daniel; Borges, Valéria Matos; Santos, Ricardo Ribeiro dos; Souza, Bruno Solano de Freitas; Soares, Milena Botelho Pereiraopen accessArticle