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Issue DateTitleAuthor(s)CopyrightType
2016Clinical Candidate VT-1161's Antiparasitic Effect In Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme CYP51 from Trypanosoma cruziHoekstra, William J.; Hargrove, Tatiana Y.; Wawrzak, Zdzislaw; Batista, Denise da Gama Jaen; Silva, Cristiane F. da; Nefertiti, Aline S. G.; Rachakonda, Girish; Schotzinger, Robert J.; Villalta, Fernando; Soeiro, Maria de Nazaré C.; Lepesheva, Galina I.open accessArticle
20174-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infectionCalvet, Claudia Magalhaes; Choi, Jun Yong; Thomas, Diane; Suzuki, Brian; Hirata, Ken; Lostracco-Johnson, Sharon; Mesquita, Liliane Batista de; Nogueira, Alanderson; Batista, Marcelo Meuser; Silva, Tatiana Araujo; Siqueira Neto, Jair Lage; Roush, William R.; Pereira, Mirian Claudia de Souza; McKerrow, James H.; Podust, Larissa M.open accessArticle
2016In Vitro and In Vivo Trypanosomicidal Action of Novel Arylimidamides against Trypanosoma cruziSilva, F. H. Guedes da; Batista, D. G. J.; Meuser, M. B.; Demarque, K. C.; Fulco, T. O.; Araújo, J. S.; Silva, P. B. da; Silva, C. F. da; Patrick, D. A.; Bakunova, S. M.; Bakunov, S. A.; Tidwell, R. R.; Oliveira, G. M.; Britto, C.; Moreira, O. C.; Soeiro, M. N. C.open accessArticle
2010Structural modelling and comparative analysis of homologous, analogous and specific proteins from Trypanosoma cruzi versus Homo sapiens: putative drug targets for chagas’ disease treatmentCapriles, Priscila V. S. Z.; Guimarães, Ana C. R.; Otto, Thomas D.; Miranda, Antonio B.; Dardenne, Laurent E.; Degrave, Wim M.open accessArticle
2010In vitro and in vivo activities of 1,3,4-thiadiazole-2-arylhydrazone derivatives of megazol against Trypanosoma cruziSalomão, K.; Souza, E. M. de; Carvalho, S. A.; Silva, E. F. da; Fraga, C. A. M.; Barbosa, H. S.; Castro, S. L. deopen accessArticle
2012In vitro and in vivo evaluation anti-Trypanosoma cruzi activity of N-acylhydrazones oxadiazolesMeira, Cássio Santana; Guimarães, Elisalva Teixeira; Bastos, Tanira Matutino; Castro, Murilo Fagundes de; Moreira, Diogo Rodrigo de Magalhães; Santos Filho, J. M. dos; Soares, Milena Botelho Pereiraopen accessPapers presented at events
2012In vitro and in vivo investigation of the efficacy of arylimidamide DB1831 and its mesylated salt form--DB1965--against Trypanosoma cruzi infectionSilva, Cristiane França da; Batista, Denise da Gama Jaen; Oliveira, Gabriel Melo; Souza, Elen Mello de; Hammer, Erica Ripoll; Silva, Patricia Bernardino da; Daliry, Anissa; Araujo, Julianna Siciliano; Britto, Constança; Rodrigues, Ana Carolina Mondaine; Liu, Zongying; Farahat, Abdelbasset A.; Kumar, Arvind; Boykin, David W.; Soeiro, Maria de Nazaré Correiaopen accessArticle
2011Would selenium supplementation aid in therapy for Chagas disease?Jelicks, Linda A.; Souza, Andréa P. de; Araujo-Jorge, Tania C.; Tanowitz, Herbert B.restricted accessArticle
2017Therapeutic effects of sphingosine kinase inhibitor N,N-dimethylsphingosine (DMS) in experimental chronic Chagas disease cardiomyopathyVasconcelos, Juliana Fraga; Meira, Cássio Santana; Silva, Daniela Nascimento; Nonaka, Carolina Kymie Vasques; Daltro, Pâmela Santana; Macambira, Simone Garcia; Domizi, Pablo Daniel; Borges, Valéria Matos; Santos, Ricardo Ribeiro dos; Souza, Bruno Solano de Freitas; Soares, Milena Botelho Pereiraopen accessArticle
2015Avaliação do efeito do benzonidazol sobre linfócitos, de portadores crônicos da doença de Chagas, submetidos experimentalmente à exposição ao Trypanosoma cruziNeves, Patrícia Areias Feitosaopen accessDissertation