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Issue DateTitleAuthor(s)CopyrightType
2010Structural modelling and comparative analysis of homologous, analogous and specific proteins from Trypanosoma cruzi versus Homo sapiens: putative drug targets for chagas’ disease treatmentCapriles, Priscila V. S. Z.; Guimarães, Ana C. R.; Otto, Thomas D.; Miranda, Antonio B.; Dardenne, Laurent E.; Degrave, Wim M.open accessArticle
2011Would selenium supplementation aid in therapy for Chagas disease?Jelicks, Linda A.; Souza, Andréa P. de; Araujo-Jorge, Tania C.; Tanowitz, Herbert B.restricted accessArticle
2016Clinical Candidate VT-1161's Antiparasitic Effect In Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme CYP51 from Trypanosoma cruziHoekstra, William J.; Hargrove, Tatiana Y.; Wawrzak, Zdzislaw; Batista, Denise da Gama Jaen; Silva, Cristiane F. da; Nefertiti, Aline S. G.; Rachakonda, Girish; Schotzinger, Robert J.; Villalta, Fernando; Soeiro, Maria de Nazaré C.; Lepesheva, Galina I.open accessArticle
20174-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infectionCalvet, Claudia Magalhaes; Choi, Jun Yong; Thomas, Diane; Suzuki, Brian; Hirata, Ken; Lostracco-Johnson, Sharon; Mesquita, Liliane Batista de; Nogueira, Alanderson; Batista, Marcelo Meuser; Silva, Tatiana Araujo; Siqueira Neto, Jair Lage; Roush, William R.; Pereira, Mirian Claudia de Souza; McKerrow, James H.; Podust, Larissa M.open accessArticle
2012In vitro and in vivo investigation of the efficacy of arylimidamide DB1831 and its mesylated salt form--DB1965--against Trypanosoma cruzi infectionSilva, Cristiane França da; Batista, Denise da Gama Jaen; Oliveira, Gabriel Melo; Souza, Elen Mello de; Hammer, Erica Ripoll; Silva, Patricia Bernardino da; Daliry, Anissa; Araujo, Julianna Siciliano; Britto, Constança; Rodrigues, Ana Carolina Mondaine; Liu, Zongying; Farahat, Abdelbasset A.; Kumar, Arvind; Boykin, David W.; Soeiro, Maria de Nazaré Correiaopen accessArticle
2017Mutagenic and Cytotoxicity LQB 123 Profile: Safety and Tripanocidal Effect of a Phenyl-t-Butylnitrone DerivativeCupello, Mauricio Peixoto; Saraiva, Francis Monique; Ippolito, Pedro; Fernandes, Andréia da Silva; Menna-Barreto, Rubem Figueiredo Sadok; Costa, Debora de Sousa dos Santos; Paula, Jessica Isis Oliveira; Costa, Paulo Roberto Ribeiro; Nogueira, Natália Pereira; Felzenswalb, Israel; Dias, Ayres Guimarães; Paes, Marcia Cristinaopen accessArticle