Author | Santos, Julia Rocha Silva | |
Author | Vendramini, Dâmia Leal | |
Author | Nery, José Augusto da Costa | |
Author | Avelleira, João Carlos Regazzi | |
Access date | 2018-02-27T11:49:26Z | |
Available date | 2018-02-27T11:49:26Z | |
Document date | 2017 | |
Citation | SANTOS, Julia Rocha Silva; et al. Etanercept in erythema nodosum leprosum. An Bras Dermatol., v.92, n.4, p.575-7, 2017. | pt_BR |
ISSN | 0365-0596 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/24954 | |
Language | eng | pt_BR |
Publisher | Sociedade Brasileira de Dermatologia | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Hanseníase | pt_BR |
Subject in Portuguese | Eritema Nodoso | pt_BR |
Subject in Portuguese | Fator de Necrose Tumoral alfa | pt_BR |
Title | Etanercept in erythema nodosum leprosum | pt_BR |
Type | Article | pt_BR |
DOI | 10.1590/abd1806-4841.20175471 | |
Abstract | One of the biggest challenges in treating leprosy is the control of reaction events. Patients with lepromatous leprosy may present reaction type II, or erythema nodosum leprosum, during treatment, and this reaction can remain in a recurrent form after being released from the hospital, requiring the use of thalidomide and/or prednisone for long periods of time, in turn increasing the risk of side effects. Two reports of the use of antiTNF to treat erythema nodosum leprosum were found in the literature. A good response was found after an assay with infliximab and etanercept. This study reports on a patient with lepromatous leprosy and recurrent reaction, controlled by using etanercept and a 10-month follow-up, with the interruption of thalidomide and the maintenance of prednisone at 10 mg/day. | pt_BR |
Affilliation | Santa Casa de Misericórdia do Rio de Janeiro. Instituto de Dermatologia Professor Rubem David Azulay. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Santa Casa de Misericórdia do Rio de Janeiro. Instituto de Dermatologia Professor Rubem David Azulay. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Santa Casa de Misericórdia do Rio de Janeiro. Instituto de Dermatologia Professor Rubem David Azulay. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Santa Casa de Misericórdia do Rio de Janeiro. Instituto de Dermatologia Professor Rubem David Azulay. Rio de Janeiro, RJ, Brasil / Hospital Federal da Lagoa. Serviço de Dermatologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Leprosy | pt_BR |
Subject | Erythema nodosum | pt_BR |
Subject | Tumor necrosis factor-alpha | pt_BR |
e-ISSN | 1806-4841 | |