Author | ZucchiI, Eliana Miura | |
Author | Couto, Marcia Thereza | |
Author | Castellanos, Marcelo | |
Author | Dumont-Pena, Érica | |
Author | Ferraz, Dulce Aurélia de Souza | |
Author | Pinheiro, Thiago Félix | |
Author | Grangeiro, Alexandre | |
Author | Silva, Luís Augusto Vasconcelos da | |
Author | Dourado, Inês | |
Author | Pedrana, Leo | |
Author | Santos, Fernanda Soares de Resendes | |
Author | Magno, Laio | |
Access date | 2021-07-26T13:26:26Z | |
Available date | 2021-07-26T13:26:26Z | |
Document date | 2021 | |
Citation | ZUCCHII, Eliana Miura et al. Acceptability of daily pre-exposure prophylaxis among adolescent men who have sex with men, travestis and transgender women in Brazil: a qualitative study. Plos One, [San Francisco], v. 16, n. 5, p.1-20, may. 2021. | pt_BR |
ISSN | 1932-6203 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/48361 | |
Sponsorship | ID and AG are principal investigators of
the PrEP 1519 Study (‘A Demonstration Project of
the effectiveness HIV Pre-exposure Prophylaxis
(PrEP) amongst adolescent men who have sex
with men, transgender women at high risk for HIV
infection in the context of Combination Prevention
in Brazil’) in the cities of Salvador and São Paulo,
respectively, which is funded by Unitaid (grant
number 2017-15-FIOTECPrEP). PrEP 1519 Study
is also funded by the Brazilian Ministry of Health,
through the Department of Chronic Diseases and
Sexually Transmitted Infections, Bahia State
Department of Health, São Paulo State and City
Department of Health, and City of São Paulo AIDS
Program, by donating PrEP medications,
condoms, and rapid tests and providing the
necessary infrastructure for the study
development. | pt_BR |
Language | eng | pt_BR |
Publisher | Public Library of Science | pt_BR |
Rights | open access | pt_BR |
MeSH | Adolescent | pt_BR |
MeSH | HIV | pt_BR |
MeSH | Sexual and Gender Minorities | pt_BR |
MeSH | Transgender Persons | pt_BR |
Title | Acceptability of daily pre-exposure prophylaxis among adolescent men who have sex with men, travestis and transgender women in Brazil: a qualitative study | pt_BR |
Type | Article | pt_BR |
DOI | 10.1371/journal.pone.0249293 | |
Abstract | Background: Adolescents face socio-structural, personal and programmatic barriers to HIV prevention services, highlighting the importance of understanding knowledge and acceptability as essential aspects to promote their broader access to pre-exposure prophylaxis (PrEP). We analyzed the acceptability of PrEP among adolescent men who have sex with men (MSM), travestis and transgender women (TGW). Methods: A qualitative investigation was conducted as part of the formative research of the PrEP15-19 study, an ongoing demonstration study that analyzes the effectiveness of daily PrEP among adolescent MSM, travestis and TGW aged 15–19 in three Brazilian cities. A total of 37 semi-structured interviews and 6 focus groups were conducted. Building from thematic analysis focusing on participants’ sexual encounters, perceptions about PrEP efficacy, and vulnerability contexts, we analyzed prospective acceptability of PrEP.
Findings: Knowledge about PrEP was incipient and characterized by adolescents’ frequent doubts about its prescription and efficacy. The ‘ideal’ use of PrEP appeared together with consistent condom use, especially in casual sex. PrEP use was also mentioned as depending on increased learning about prevention management over time. Main barriers to PrEP use included the incorporation of a daily medication into participants’ routine and its impact on their social lives, especially related to stigma. Concerns over short- and long-term side effects were also reported as barriers to PrEP use. TGW and travestis contrasted using PrEP with the precarity of their life conditions, and some expressed a critical vision about PrEP by associating it with pharmaceuticalization and trans necropolitics. Conclusions:
Participants’ low knowledge and acceptability of PrEP are circumscribed by a rigid perception of condom as the ideal prevention method and the context of their sexual relations. Prospective acceptability highlights that the successful uptake of PrEP depends on overcoming barriers of access to health services and confronting transphobia and homophobia as part of care. | pt_BR |
Affilliation | Universidade Católica de Santos. Programa de Pós-Graduação Profissional em Psicologia e Políticas Públicas. Santos, SP, Brasil / Universidade Católica de Santos. Programa de Pós-Graduação em Saúde Coletiva. Santos, SP, Brasil | pt_BR |
Affilliation | Universidade de São Paulo. Faculdade de Medicina. São Paulo, SP, Brasil. | pt_BR |
Affilliation | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil. | pt_BR |
Affilliation | Universidade Federal de Minas Gerais. Departamento de Enfermagem Materno Infantil e Saúde Pública. Belo Horizonte, MG, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Escola Fiocruz de Governo. Brasília, DF, Brasil. | pt_BR |
Affilliation | Universidade de São Paulo. Faculdade de Medicina. São Paulo, SP, Brasil. | pt_BR |
Affilliation | Universidade de São Paulo. Faculdade de Medicina. São Paulo, SP, Brasil. | pt_BR |
Affilliation | Universidade Federal da Bahia. Instituto de Humanidades, Artes e Ciências, Salvador, BA, Brasil. | pt_BR |
Affilliation | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil. | pt_BR |
Affilliation | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil. | pt_BR |
Affilliation | Universidade Federal de Minas Gerais. Programa de Pós-Graduação em Enfermagem. Belo Horizonte, MG, Brasil. | pt_BR |
Affilliation | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil / Universidade do Estado da Bahia. Departamento de Ciências da Vida. Salvador, BA, Brasil. | pt_BR |
Subject | Adolescents | pt_BR |
Subject | HIV | pt_BR |
Subject | Sexual and gender minorities | pt_BR |
Subject | Transgender persons | pt_BR |
Subject | HIV prevention | pt_BR |
DeCS | Adolescente | pt_BR |
DeCS | HIV | pt_BR |
DeCS | Minorias Sexuais e de Gênero | pt_BR |
DeCS | Pessoas Transgênero | pt_BR |
DeCS | Prevenção de Doenças | pt_BR |