Browsing by Subject "Drug repurposing"

Activity of mefloquine and mefloquine derivatives against Echinococcus multilocularis

Rufener, Reto et al. | Date Issued: 2018

Arsenic trioxide triggers apoptosis of metastatic oral squamous cells carcinoma with concomitant downregulation of gli1 in hedgehog signaling

Nogueira, Raphael Luís Rocha et al. | Date Issued: 2022

COVID-19: molecular targets, drug repurposing and new avenues for drug discovery

Senger, Mario Roberto et al. | Date Issued: 2020

Drug repurposing for Chagas disease: In vitro assessment of nimesulide against Trypanosoma cruzi and insights on its mechanisms of action

Trindade, Joana D’Arc S. et al. | Date Issued: 2021

Effect of Itraconazole-Ezetimibe-Miltefosine Ternary Therapy in Murine Visceral Leishmaniasis

Andrade Neto, Valter V. et al. | Date Issued: 2021

Efficacy of sertraline against Trypanosoma cruzi: an in vitro and in silico study

Ferreira, Daiane Dias et al. | Date Issued: 2018

Identification of Hypericin as a Candidate Repurposed Therapeutic Agent for COVID-19 and Its Potential Anti-SARS-CoV-2 Activity

Matos, Aline da Rocha et al. | Date Issued: 2022

In silico approaches for drug repurposing in oncology: a scoping review

Cavalcante, Bruno Raphael Ribeiro et al. | Date Issued: 2024

In vitro activity of the anthelmintic drug niclosamide against Sporothrix spp. strains with distinct genetic and antifungal susceptibility backgrounds

Ramos, Mariana Lucy Mesquita et al. | Date Issued: 2024

In vitro antifungal activity of MMV Pathogen Box® compounds alone or in combination with antifungal drugs against mucormycosis agents

Almeida-Silva, Fernando et al. | Date Issued: 2024

Medicines for Malaria Venture COVID Box: a source for repurposing drugs with antifungal activity against human pathogenic fungi

Paes, Rodrigo de Almeida et al. | Date Issued: 2021

Mefloquine synergism with anti-tuberculosis drugs and correlation to membrane effects: Biologic, spectroscopic and molecular dynamics simulations studies

Santos, Marinalva Cardoso dos et al. | Date Issued: 2021

New drug candidates for osteosarcoma: Drug repurposing based on gene expression signature

Andrade, Raissa Coelho et al. | Date Issued: 2021

New possibilities for chromoblastomycosis and phaeohyphomycosis treatment: identification of two compounds from the MMV Pathogen Box® that present synergism with itraconazole

Coelho, Rowena Alves et al. | Date Issued: 2022

Repurposing strategies for Chagas disease therapy: the effect of imatinib and derivatives against Trypanosoma cruzi

Silva, M. R. Simões et al. | Date Issued: 2019

Structural characterization of heat shock protein 90β and molecular interactions with Geldanamycin and Ritonavir: a computational study

Lima, Carlyle Ribeiro et al. | Date Issued: 2024

The pulmonary route as a way to drug repositioning in COVID-19 therapy

Sarcinelli, MIchelle Alvares et al. | Date Issued: 2021

Unveiling the Kinomes of Leishmania infantum and L. braziliensis Empowers the Discovery of New Kinase Targets and Antileishmanial Compounds

Borba, Joyce Villa Verde Bastos et al. | Date Issued: 2019