| Author | Goulart, Alessandra C. | |
| Author | Santos, Itamar S. | |
| Author | Brunoni, André R. | |
| Author | Nunes, Maria Angélica | |
| Author | Passos, Valéria M. | |
| Author | Griep, Rosane Harter | |
| Author | Lotufo, Paulo A. | |
| Author | Bensenor, Isabela M | |
| Access date | 2015-05-15T13:16:41Z | |
| Available date | 2015-05-15T13:16:41Z | |
| Document date | 2014 | |
| Citation | GOULART, Alessandra C. et al. Migraine Headaches and Mood/Anxiety Disorders in the ELSA Brazil. Headache: The Journal of Head and Face Pain, v.54, n.8, p.1310-1319, sept. 2014 | pt_BR |
| ISSN | 0017-8748 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/10317 | |
| Language | eng | pt_BR |
| Publisher | Wiley Periodicals, Inc. | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Epidemiologia | pt_BR |
| Subject in Portuguese | Transtornos de Enxaqueca | pt_BR |
| Subject in Portuguese | Enxaqueca | pt_BR |
| Title | Migraine Headaches and Mood/Anxiety Disorders in the ELSA Brazil | pt_BR |
| Type | Article | |
| DOI | 10.1111/head.12397 | pt_BR |
| Abstract | Objective.—To describe the relationship between mood/anxiety disorders and migraine headaches emphasizing the
frequency of episodes based in a cross-sectional analysis in the Brazilian Longitudinal Study of Adult Health.
Background.—It has been suggested that frequency of migraine headaches can be directly associated with the presence of
psychiatric disorders.
Methods.—Migraine headaches (International Headache Society criteria) was classified as <1×/month, 1×/month-1×/week,
2-6×/week, and daily. Psychiatric disorders using the Clinical Interview Schedule – Revised were classified in 6 categories:
common mental (CMD), major depressive (MDD), generalized anxiety (GAD), panic, obsessive-compulsive (OCD), and
mixed anxiety and depressive (MADD) disorders.We performed multivariate logistic models adjusted for age, race, education,
marital status, income, and use of selective serotonin reuptake inhibitors.
Results.—In our sample, 1261 presented definite migraine and 10,531 without migraine headaches (reference). Our main
result was an increase in the strength of association between migraine and MDD as frequency of migraine increased for all
sample: odds ratio of 2.14 (95% confidence interval [CI] 1.33-3.43) for <1 episode of migraine/month to 6.94 (95% CI
4.20-11.49) for daily headaches for all sample. Significant associations with migraine were also found for GAD, OCD, MADD,
and CMD for total sample: MDD, GAD, OCD, MADD, and CMD for women, and MADD and CMD for men. Among men
with daily migraine complaint, we found a significant association between migraine and OCD after correction for multiple
comparisons (odds ratio 29.86 [95% CI 4.66-191.43]). Analyzing probable and definite migraine cases together, we replicated
the findings in a lower magnitude.
Conclusions.—The increase in migraine frequency was associated with progressively higher frequencies of having mood/
anxiety disorders in all samples suggesting for some psychiatric disorders a likely dose-response effect especially for women. | pt_BR |
| Affilliation | Universidade de São Paulo. Hospital Universitário. São Paulo, SP, Brasil. | pt_BR |
| Affilliation | Universidade de São Paulo. Faculdade de Medicina. Hospital Universitário. São Paulo, SP, Brasil. | pt_BR |
| Affilliation | Universidade de São Paulo. Hospital Universitário. São Paulo, SP, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio Grande do Sul. Porto Alegre, RS, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Educação em Ambiente e Saúde. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade de São Paulo. Faculdade de Medicina. Hospital Universitário. São Paulo, SP, Brasil. | pt_BR |
| Affilliation | Universidade de São Paulo. Faculdade de Medicina. Hospital Universitário. São Paulo, SP, Brasil. | pt_BR |
| Subject | Migraine | pt_BR |
| Subject | Mood disorder | pt_BR |
| Subject | Epidemiology | pt_BR |
| Subject in Spanish | Trastornos Migrañosos | pt_BR |
| Subject in Spanish | Epidemiologia | pt_BR |
