| Author | Madeira, Maria F. | pt_BR |
| Author | Almeida, Arleana B. B. F. | pt_BR |
| Author | Barros, Juliana H. S. | pt_BR |
| Author | Oliveira, Tatiana S. F. | pt_BR |
| Author | Sousa, Valeria R. F. | pt_BR |
| Author | Alves, Andreia S. | pt_BR |
| Author | Miranda, Luciana F. C. | pt_BR |
| Author | Schubach, Armando O. | pt_BR |
| Author | Marzochi, Mauro C. A. | pt_BR |
| Access date | 2015-06-24T12:26:35Z | |
| Available date | 2015-06-24T12:26:35Z | |
| Document date | 2014 | |
| Citation | MADEIRA, Maria F. et al. Trypanosoma caninum, a New Parasite Described in Dogs in Brazil: Aspects of Natural Infection. Journal of Parasitology, v. 100, n. 2, p. 231-234, 2014. | pt_BR |
| ISSN | 1937-2345 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/10955 | |
| Sponsorship | This study was funded in part by grants from PAPES VI (CNPq, process no. 407700/2012-9), Fundação de Amparo a Pesquisa do estado do Rio de Janeiro (FAPERJ, 26102321-2009), and Fundação de Amparo a Pesquisa do estado de Mato Grosso (FAPEMAT). M. C. A. Marzochi and A. Schubach are the recipients of fellowships from CNPq. | pt_BR |
| Language | eng | pt_BR |
| Publisher | BioOne | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Cães | pt_BR |
| Subject in Portuguese | Brasil | pt_BR |
| Title | Trypanosoma caninum, a New Parasite Described in Dogs in Brazil: Aspects of Natural Infection | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1645/13-297.1 | pt_BR |
| Abstract | Trypanosoma caninum constitutes the most recent trypanosomatid species infecting dogs in Brazil. Due to the limited data available about this parasite, this study aims to disclose clinical and laboratory findings from 14 dogs naturally infected. The dogs were diagnosed during a cross-sectional survey in Cuiabá (Mato Grosso, Brazil) and followed up at an interval of 3, 6, and 12 mo in order to evaluate the clinical evolution and to investigate the parasite, the DNA, or both in different biological samples (intact skin, cutaneous scar, blood, bone marrow, and lymph node aspirate) by parasitological (culture and smear exam) and molecular (DNA-based tests) methods. Specific anti-T. caninum and anti-Leishmania antibody production was also evaluated. Ten of 14 dogs infected by T. caninum showed a good general state at the time of diagnosis, and this status did not vary during the follow-up. Anti-T. caninum and anti-Leishmania IgG antibodies were detected by IFAT in 10 and 2 animals, respectively. Concomitant infection by Leishmania chagasi was confirmed in 2 dogs, indicating an overlap of endemic areas in Cuiabá. Trypanosoma caninum (parasite or DNA) was found only in the intact skin in all animals examined. Our results suggest that T. caninum infection can be manifested as an asymptomatic case with low humoral immune response. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Vigilância em Leishmaniose. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Vigilância em Leishmaniose. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Vigilância em Leishmaniose. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Vigilância em Leishmaniose. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Vigilância em Leishmaniose. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Vigilância em Leishmaniose. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Vigilância em Leishmaniose. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Vigilância em Leishmaniose. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Vigilância em Leishmaniose. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Trypanosoma cruzi | pt_BR |
| Subject | Dogs | pt_BR |
| Subject | Visceral leishmaniasis | pt_BR |
| Subject | Brazil | pt_BR |
| DeCS | Trypanosoma cruzi | pt_BR |
| DeCS | Leishmaniose Visceral | pt_BR |
