| Author | Oliveira, Fernanda da Silva | |
| Author | Rodrigues, Frederico Villas Boas | |
| Author | Demarque, Kelly Cristina | |
| Author | Rangel, Janaína Alves | |
| Author | Alvarenga, Tathiana A | |
| Author | Batista, Wanderson Silva | |
| Author | Gameiro, Lucas dos Santos | |
| Author | Oliveira, Gabriel de | |
| Access date | 2015-06-24T12:26:36Z | |
| Available date | 2015-06-24T12:26:36Z | |
| Document date | 2013 | |
| Citation | OLIVEIRA, Fernanda da Silva et al. Characterization of dominant and subordinate social status and the structure of the social hierarchy in swiss webster mice. RESBCAL, v.2 n.2, p.136-146, 2013. | pt_BR |
| ISSN | 2238-1589 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/10958 | |
| Language | eng | pt_BR |
| Publisher | Sociedade Brasileira de Ciência em Animais de Laboratório | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Camundongos | pt_BR |
| Subject in Portuguese | Comportamento agressivo | pt_BR |
| Title | Characterization of dominant and subordinate social status and the structure of the social hierarchy in swiss webster mice | pt_BR |
| Type | Article | |
| Abstract | The mice used in animal facilities belong to the family Muridae, subfamily Murinae,
order Rodentia, genus Mus and species Mus musculus. They are social and territorial
animals. Several lineages developed in the laboratory show aggressive behavior similar
to that of wild mice. The aim of this study was characterize the hierarchical structure,
body characteristics and hormonal levels in dominant, subordinate and non-aggressive
mice. The model established for spontaneous aggression (MSA) evaluates the pattern of
aggressive behavior (PBA) and categorizes the animals as follows: LAg - individuals with
low aggressive behavior, HAg – dominant (highly aggressive) and Sb - subordinate. The
regrouping of adult male mice produces substantial stress and influences the formation
of their hierarchical structure. Behavioral comparisons before regrouping (BfR) and after
regrouping showed that the percentage of body weight lost in mice was dependent
of the specific categories as follows: LAg - 68.1%, HAg - 86.9% and Sb - 90.5%; the
average corticosterone levels by category were BfR: 43.5±17.5, LAg: 177.0±40.4, HAg:
72.8±23.8 and Sb: 136.4±51.2 ng/mL. Dominant mice showed differences in body
characteristics (primarily the body/tail relationship) relative to subordinate mice. Two
additional hierarchical positions were observed: “neutral individual” (without aggressive
behavior) and “subordinate target” (an animal that receives approximately 30% of the
total number of attacks made by dominant animals). | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Celular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Celular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Celular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Celular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal de São Paulo /UNIFESP. Departamento de Psicobiologia. São Paulo, SP, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Celular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Inovações em Terapias, Ensino e Bioprodutos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Celular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Mice | pt_BR |
| Subject | Aggressive Behavior | pt_BR |
| Subject | Social Hierarchy | pt_BR |
| Subject | Stress | pt_BR |
| Subject | Steroid Corticosterone | pt_BR |
