Author | Lopes, Marien Siqueira Soto | |
Author | Trope, Beatriz Moritz | |
Author | Rodriguez, Maria Paula Rua Rochedo | |
Author | Grynszpan, Rachel Lima | |
Author | Cuzzi, Tullia | |
Author | Silva, Marcia Ramos e | |
Access date | 2015-06-29T16:43:08Z | |
Available date | 2015-06-29T16:43:08Z | |
Document date | 2013 | |
Citation | LOPES, Marien Siqueira Soto et al. Paradoxical reaction to golimumab: tumor necrosis factor α inhibitor inducing psoriasis pustulosa. Case Reports in Dermatology, v.5, n.3, p.326–331, 2013. | pt_BR |
ISSN | 1662-6567 | |
URI | https://www.arca.fiocruz.br/handle/icict/11001 | |
Language | eng | pt_BR |
Publisher | Karger | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Golimumab | pt_BR |
Subject in Portuguese | Reação paradoxal | pt_BR |
Title | Paradoxical reaction to golimumab: tumor necrosis factor α inhibitor inducing psoriasis pustulosa | pt_BR |
Type | Article | pt_BR |
DOI | 10.1159/000350930 | |
Abstract | Golimumab is a human monoclonal antibody, used for rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis. Adverse reactions are increasing with this class of medication (tumor necrosis factor α inhibitors). Observations: The authors present a case of a female patient who presented with psoriasis pustulosa after the use of golimumab for rheumatoid arthritis. Conclusions and Relevance: Paradoxically, in this case, golimumab, which is used for psoriasis, induced the pustular form of this disease. We are observing an increasing number of patients who develop collateral effects with tumor necrosis factor α inhibitors, and the understanding of the mechanism of action and how these adverse reactions occur may contribute to avoid these sometimes severe situations. | pt_BR |
Affilliation | Universidade Federal do Rio de Janeiro. Hospital Universitário Clementino Fraga Filho. Escola de Medicina. Setor de Dermatologia. Rio de Janeiro, RJ, Brasil | pt_BR |
Affilliation | Universidade Federal do Rio de Janeiro. Hospital Universitário Clementino Fraga Filho. Escola de Medicina. Setor de Dermatologia. Rio de Janeiro, RJ, Brasil | pt_BR |
Affilliation | Universidade Federal do Rio de Janeiro. Hospital Universitário Clementino Fraga Filho. Escola de Medicina. Setor de Dermatologia. Rio de Janeiro, RJ, Brasil | pt_BR |
Affilliation | Universidade Federal do Rio de Janeiro. Hospital Universitário Clementino Fraga Filho. Escola de Medicina. Setor de Dermatologia. Rio de Janeiro, RJ, Brasil | pt_BR |
Affilliation | Universidade Federal do Rio de Janeiro. Hospital Universitário Clementino Fraga Filho. Faculdade de Medicina. Rio de Janeiro, RJ, Brasil | pt_BR |
Affilliation | Universidade Federal do Rio de Janeiro. Hospital Universitário Clementino Fraga Filho. Escola de Medicina. Setor de Dermatologia. Rio de Janeiro, RJ, Brasil | pt_BR |
Subject | Psoriasis | pt_BR |
Subject | Tumor Necrosis Factor-alpha | pt_BR |
Subject | Immunosuppressive Agents | pt_BR |
Subject | Arthritis, Rheumatoid | pt_BR |
DeCS | Psoríase | pt_BR |
DeCS | Fator de Necrose Tumoral alfa | pt_BR |
DeCS | Imunossupressores | pt_BR |
DeCS | Artrite Reumatoide | pt_BR |
e-ISSN | 1662-6567 | |