| Author | Volf, Petr | |
| Author | Nogueira, Paula Monalisa | |
| Author | Myskova, Jitka | |
| Author | Turco, Salvatore J. | |
| Author | Soares, Rodrigo Pedro Pinto | |
| Access date | 2015-07-08T13:09:24Z | |
| Available date | 2015-07-08T13:09:24Z | |
| Document date | 2014 | |
| Citation | VOLF, Petr et al. Structural comparison of lipophosphoglycan from Leishmania turanica. and L. major, two species transmitted by Phlebotomus papatasi Parasitology International, vol. 63, p. 683–686, 2014. | pt_BR |
| ISSN | 1383-5769 | |
| URI | https://www.arca.fiocruz.br/handle/icict/11163 | |
| Language | eng | pt_BR |
| Publisher | Elsevier Ireland Ltd. | pt_BR |
| Rights | restricted access | pt_BR |
| Title | Structural comparison of lipophosphoglycan from Leishmania turanica and L. major, two species transmitted by Phlebotomus papatasi | pt_BR |
| Type | Article | |
| DOI | 10.1016/j.parint.2014.05.004 | |
| Abstract | The lipophosphoglycan (LPG) of Leishmania major has a major role in the attachment to Phlebotomus papatasi midgut.Here,we investigated the comparative structural features of LPG of L. turanica, another species transmitted by P. papatasi. ThemAbWIC 79.3, specific for terminalGal(β1,3) side-chains, strongly reactedwith L. turanica LPG. In contrast, L. turanica LPG was not recognized by arabinose-specific mAb 3F12. In conclusion, LPGs from L. major and L. turanica are similar, with the latter being less arabinosylated than L. major's. The high galactose content in L. turanica LPG is consistent with its predicted recognition by P. papatasi lectin PpGalec. | pt_BR |
| Affilliation | Charles University Faculty of Science. Department of Parasitology. Prague, Czech Republic | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | Charles University Faculty of Science. Department of Parasitology. Prague, Czech Republic | pt_BR |
| Affilliation | University of Kentucky Medical Center. Department of Biochemistry. Lexington, KY, USA | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brazil | pt_BR |
| Subject | Leishmania turanica | pt_BR |
| Subject | LPG | pt_BR |
| Subject | Sand fly–Leishmania | pt_BR |
| Subject | interaction | pt_BR |
| Subject | Phlebotomus papatasi | pt_BR |
