| Author | Spitz, Natália | |
| Author | Mello, Francisco C. A. | |
| Author | Araujo, Natalia Motta | |
| Access date | 2015-08-19T13:49:24Z | |
| Available date | 2015-08-19T13:49:24Z | |
| Document date | 2015 | |
| Citation | SPITZ, Natália; MELLO, Francisco C. A.; ARAUJO, Natalia Motta. Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region. Mem Inst Oswaldo Cruz, v.110, n.1, p.151-153, Feb, 2015. | pt_BR |
| ISSN | 1678-8060 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/11507 | |
| Language | eng | pt_BR |
| Publisher | Fundação Oswaldo Cruz | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Região Amazônica | pt_BR |
| Title | Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region | pt_BR |
| Type | Article | |
| DOI | 10.1590/0074-02760140426 | pt_BR |
| Abstract | The Brazilian Amazon Region is a highly endemic area for hepatitis B virus (HBV). However, little is known
regarding the genetic variability of the strains circulating in this geographical region. Here, we describe the first
full-length genomes of HBV isolated in the Brazilian Amazon Region; these genomes are also the first complete HBV
subgenotype D3 genomes reported for Brazil. The genomes of the five Brazilian isolates were all 3,182 base pairs
in length and the isolates were classified as belonging to subgenotype D3, subtypes ayw2 (n = 3) and ayw3 (n = 2).
Phylogenetic analysis suggested that the Brazilian sequences are not likely to be closely related to European D3
sequences. Such results will contribute to further epidemiological and evolutionary studies of HBV. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal Fluminense. Departamento de Microbiologia e Parasitologia. Niterói, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | HBV | pt_BR |
| Subject | Complete genome | pt_BR |
| Subject | Amino acid residues | pt_BR |
| Subject | Genetic distance | pt_BR |
| Subject | subgenotype D3 | pt_BR |
| DeCS | Vírus da Hepatite B | pt_BR |
| DeCS | Genótipo | pt_BR |
