| Author | Gentile, Carla | |
| Author | Rivas, Gustavo Bueno da S. | |
| Author | Lima, José B. P. | |
| Author | Bruno, Rafaela Vieira | |
| Author | Peixoto, Alexandre Afrânio | |
| Access date | 2015-08-19T13:49:33Z | |
| Available date | 2015-08-19T13:49:33Z | |
| Document date | 2013 | |
| Citation | GENTILE, Carla; et al. Circadian clock of Aedes aegypti: effects of blood-feeding, insemination and RNA interference. Mem Inst Oswaldo Cruz, v.108, Suppl. I, p.80-87, 2013. | pt_BR |
| ISSN | 1678-8060 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/11565 | |
| Language | eng | pt_BR |
| Publisher | Fundação Oswaldo Cruz | pt_BR |
| Rights | open access | |
| Title | Circadian clock of Aedes aegypti: effects of blood-feeding, insemination and RNA interference | pt_BR |
| Type | Article | |
| DOI | 10.1590/0074-0276130471 | pt_BR |
| Abstract | Mosquitoes are the culprits of some of the most important vector borne diseases. A species’ potential as a vector
is directly dependent on their pattern of behaviour, which is known to change according to the female’s physiological
status such as whether the female is virgin/mated and unfed/blood-fed. However, the molecular mechanism triggered
by and/or responsible for such modulations in behaviour is poorly understood. Clock genes are known to be responsible
for the control of circadian behaviour in several species. Here we investigate the impact mating and blood-feeding
have upon the expression of these genes in the mosquito Aedes aegypti. We show that blood intake, but not insemination,
is responsible for the down-regulation of clock genes. Using RNA interference, we observe a slight reduction in
the evening activity peak in the fourth day after dstim injection. These data suggest that, as in Drosophila, clock gene
expression, circadian behaviour and environmental light regimens are interconnected in Ae. aegypti. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. 3Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ, Brasil / Instituto de Biologia do Exército. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular. Rio de Janeiro, RJ, Bra | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular. Rio de Janeiro, RJ, Bra | pt_BR |
| Subject | Clock genes | pt_BR |
| Subject | Blood feeding | pt_BR |
| Subject | Insemination | pt_BR |
| Subject | RNAi | pt_BR |
| Subject | Behaviour | pt_BR |
| Subject | Aedes aegypti | pt_BR |
| DeCS | Aedes | pt_BR |
| DeCS | Inseminação | pt_BR |
| DeCS | Comportameto | pt_BR |
| DeCS | Culicidae | pt_BR |
