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| Fecha de acceso | 2015-11-19T17:53:14Z | |
| Fecha de disponibilización | 2015-11-19T17:53:14Z | |
| Fecha de publicación | 2009 | |
| Referencia | NEGRÉ, Jose Maria Suñe; GRAU, Jose Ramon Ticó. Solid phamaceutical composition of didanosine. WO2009063320 A2, 13 nov. 2008. 19p. | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/12294 | |
| Idioma | spa | pt_BR |
| Derechos de autor | open access | pt_BR |
| Título | Solid pharmaceutical composition of didanosine | pt_BR |
| Tipo del documento | Patent | pt_BR |
| Resumen en Inglés | The present invention relates to a new solid pharmaceutical composition of didanosine comprising didanosine crystals with an average particle size comprised between 50 and 500 microns, coated by a layer of an enteric coating. The pharmaceutical composition of the invention can be prepared by means of a simple process, which comprises coating the didanosine crystals with an enteric layer. Said composition has a good stability of the active ingredient, as well as a suitable release in the conditions present in the upper part of the gastrointestinal tract. It also relates to the use of said composition for preparing solid dosage forms of didanosine for their oral administration. The invention also relates to tablets and to hard gelatin capsules containing said composition. | pt_BR |
| Afiliación | Blanver Farmoquímica Ltda. Cotia, SP, Brasil. | pt_BR |
| Afiliación | Blanver Farmoquímica Ltda. Cotia, SP, Brasil. | pt_BR |
| Inventor | Jose Maria Suñe Negré | pt_BR |
| Inventor | Jose Ramon Ticó Grau | pt_BR |
| Institución títular de la patente | Fundação Oswaldo Cruz. Brasil. | pt_BR |
| Institución títular de la patente | Blanver Farmoquímica Ltda. Brasil. | pt_BR |
| Fecha de publicación | 2009-05-22 | |
| Numero IPC | A61K 9/16 | |
| Numero IPC | A61K 9/50 | |
| Numero IPC | A61K 31/505 | |
| Numero de deposito | PCT/IB2008/003527 | pt_BR |
| Numero de deposito de la prioridad | ES200703002 | pt_BR |
| Fecha de depósito | 2008-11-13 | |
| Numero de publicación | WO2009063320 A2 | pt_BR |
| Pais registro de la patente | Espanha | pt_BR |
| Pais registro de la patente | PCT | pt_BR |
| Pais registro de la patente | Europa | pt_BR |
| Pais registro de la patente | Brasil | pt_BR |
| País(es) de concesión de la patente | Espanha | pt_BR |
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