| Author | Tendler, Miriam | |
| Author | Almeida, Marilia | |
| Author | Simpson, Andrew | |
| Access date | 2016-03-17T14:35:34Z | |
| Available date | 2016-03-17T14:35:34Z | |
| Document date | 2015 | |
| Citation | TENDLER, Miriam; ALMEIDA, Marilia; SIMPSON, Andrew. Development of the Brazilian anti Schistosomiasis vaccine based on the recombinant fatty acid binding protein Sm14 plus GLA-SE adjuvant. Frontiers in Immunology, v.6:218, 6p, May 2015. | pt_BR |
| ISSN | 1664-3224 | |
| URI | https://www.arca.fiocruz.br/handle/icict/13197 | |
| Language | eng | pt_BR |
| Publisher | Frontiers Media | pt_BR |
| Rights | open access | |
| Title | Development of the Brazilian anti Schistosomiasis vaccine based on the recombinant fatty acid binding protein Sm14 plus GLA-SE adjuvant | pt_BR |
| Type | Article | |
| DOI | 10.3389/fimmu.2015.00218 | |
| Abstract | Data herein reported and discussed refer to vaccination with the recombinant fatty acid
binding protein (FABP) family member of the schistosomes, called Sm14. This antigen was
discovered and developed under a Brazilian platform led by the Oswaldo Cruz Foundation,
from the Health Ministry in Brazil, and was assessed for safety and immunogenicity
in healthy volunteers. This paper reviews past and recent outcomes of developmental
phases of the Sm14-based anti schistosomiasis vaccine addressed to, ultimately, impact
transmission of the second most prevalent parasitic endemic disease worldwide. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Orygen Biotecnologia. São Paulo, SP, Brasil. | pt_BR |
| Subject | Vaccine | pt_BR |
| Subject | Schistosomiasis | pt_BR |
| Subject | Sm14 | pt_BR |
| Subject | Disease of poverty | pt_BR |
| Subject | FABP | pt_BR |
| Subject | Brazil | pt_BR |
| DeCS | Esquistossomose | pt_BR |
| DeCS | Brasil | pt_BR |
| DeCS | Vacina | pt_BR |
| xmlui.metadata.dc.subject.ods | 1 Erradicação da pobreza | |
