| Author | Nascimento, Kenia Kelly Fiaux do | |
| Author | Pereira, Kelly Silva | |
| Author | Firmo, Josélia Oliveira Araújo | |
| Author | Costa, Maria Fernanda Lima | |
| Author | Diniz, Breno Satler de Oliveira | |
| Author | Costa, Erico Castro | |
| Access date | 2016-04-06T18:53:45Z | |
| Available date | 2016-04-06T18:53:45Z | |
| Document date | 2015 | |
| Citation | NASCIMENTO, Kenia Kelly Fiaux do et al. Predictors of incidence of clinically significant depressive symptoms in the elderly: 10-year follow-up study of the Bambui cohort study of aging. International Journal of Geriatric Psychiatry, vol. 30, n. 12, p. 1171–1176, 2015 | pt_BR |
| ISSN | 1099-1166 | |
| URI | https://www.arca.fiocruz.br/handle/icict/13592 | |
| Language | eng | pt_BR |
| Publisher | Wiley Online Library | pt_BR |
| Rights | restricted access | pt_BR |
| Title | Predictors of incidence of clinically significant depressive symptoms in the elderly: 10-year follow-up study of the Bambui cohort study of aging. | pt_BR |
| Type | Article | |
| Abstract | Objective: We aim to evaluate the incidence rate and predictors of clinically significant depressive symptoms (CSDS) over 10 years of follow-up from a population-based cohort study (the Bambui Cohort Study of Aging).
Methods: We calculated the predictors of incidence of CSDS over 10 years of follow-up by the Cox proportional regression analysis. Depressive symptoms were evaluated by GHQ-12 and scores of five or higher indicated CSDS.
Results: The annualized incidence rate of clinically significant depressive symptoms was 46 per 1000 person-year. In the multivariate analysis, the main predictors of CSDS were cognitive impairment (HR = 1,69 CI95% [1,20 – 2.37], p = 0.002), diabetes (HR = 1.59 CI95% [1.14 – 2.20], p = 0.006), use of 2 to 4 (HR = 1,95 CI95% [1.21 – 3.15], p = 0.006) and of 5 or more medications in the last 90 days (HR = 2.19 CI95% [1.31 – 3.66], p = 0.003) and higher baseline depressive symptoms (HR = 2.12 CI95% [1.61 – 2.78], p < 0.001).
Conclusion: These results highlight the importance of higher depressive symptoms, cognitive impairment and endocrine-metabolic disorders to the development of depressive symptoms in older adults. These findings provide a framework for the development of interventions to prevent the emergence of clinically significant depressive symptoms in the elderly. | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Faculdade de Medicina. Laboratorio de Investigação em Neurociencia Clinica. Belo Horizonte, MG, Brasil | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Faculdade de Medicina. Laboratorio de Investigação em Neurociencia Clinica. Belo Horizonte, MG, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, Brasil/Universidade Federal de Minas Gerais. Faculdade de Medicina. Departamento de Medicina Social e Preventiva. Belo Horizonte, MG, Brasil | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Faculdade de Medicina. Laboratorio de Investigação em Neurociencia Clinica. Belo Horizonte, MG, Brasil/Fundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, Brasil/Universidade Federal de Minas Gerais. Faculdade de Medicina. Departamento de Medicina Social e Preventiva. Belo Horizonte, MG, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, Brasil | pt_BR |
| Subject | late-life depressive symptoms | pt_BR |
| Subject | incidence | pt_BR |
| Subject | cohort studies | pt_BR |
| Subject | risk factors | pt_BR |
