| Author | Bittencourt, Achilea Candida Lisboa | pt_BR |
| Author | Barral, Aldina Maria Prado | pt_BR |
| Author | Costa, Jackson Mauricio Lopes | pt_BR |
| Author | Saldanha, Ana Cristina | pt_BR |
| Author | Badaró, Fernando | pt_BR |
| Author | Barral Netto, Manoel | pt_BR |
| Author | Freitas, Luiz Antonio Rodrigues de | pt_BR |
| Access date | 2016-07-04T19:45:13Z | pt_BR |
| Access date | 2016-07-14T19:07:30Z | |
| Available date | 2016-07-04T19:45:13Z | pt_BR |
| Available date | 2016-07-14T19:07:30Z | |
| Document date | 1992 | |
| Citation | BITTENCOURT, A. C. L. et al. Diffuse Cutaneous Leishmaniasis with atypical aspects. International Journal of Dermatology, v. 31, n. 8, p. 568-570, 1992. | pt_BR |
| ISSN | 0011-9059 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/14913 | |
| Language | eng | pt_BR |
| Publisher | Wiley | pt_BR |
| Rights | open access | pt_BR |
| Title | Diffuse Cutaneous Leishmaniasis with atypical aspects | pt_BR |
| Type | Article | pt_BR |
| Abstract | A 16-year-old man had long-standing diffuse cutaneous
leishmaniasis with the following characteristics: diffuse infiltrated
lesions rich in amastigotes, absence of mucosal involvement,
and lack of parasite-specific cell-mediated immune
response. In situ identification of Leishmania mexicana amazonensis
was achieved by the use of monoclonal antibodies.
Clinically, as an atypical finding there was deep and extensive
ulceration in the lower limbs. Histologically, an atypical
characteristic was the presence of a high number of eosinophils
in the infiltrate predominantly in the ulcerated lesion.
Ultrastructurally, parasitized and lysed eosinophils with
dispersion of their granules were seen in the vicinity of parasitized
or lysed macrophages. | pt_BR |
| Affilliation | Universidade Federal da Bahia. Faculdade de Medicina. Departamento de Patologia e Medicina Interna. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Gonçalo Moniz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Universidade Federal do Maranhão. Escola de Medicina. Departamento de Doenças Infecciosas e Parasitárias. São Luis, MA, Brasil | pt_BR |
| Affilliation | Universidade Federal da Bahia. Faculdade de Medicina. Departamento de Patologia e Medicina Interna. Salvador, BA, Brasil | pt_BR |
| Affilliation | Universidade Federal da Bahia. Faculdade de Medicina. Departamento de Patologia e Medicina Interna. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Gonçalo Moniz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Gonçalo Moniz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Subject | Leishmaniasis, Diffuse Cutaneous | pt_BR |
| Subject | Parasites | pt_BR |
| Subject | Eosinophils | pt_BR |
| Subject | Cutaneous Leishmaniasis | pt_BR |
| Subject | Humans | pt_BR |
