| Author | Coutinho-Neto, Antonio | pt_BR |
| Author | Caldeira, Cleópatra A. S. | pt_BR |
| Author | Souza, Gustavo H. M. F. | pt_BR |
| Author | Zaqueo, Kayena D. | pt_BR |
| Author | Kayano, Anderson M. | pt_BR |
| Author | Silva, Rodrigo S. | pt_BR |
| Author | Zuliani, Juliana P. | pt_BR |
| Author | Soares, Andreimar M. | pt_BR |
| Author | Stábeli, Rodrigo G. | pt_BR |
| Author | Calderon, Leonardo A. | pt_BR |
| Access date | 2016-07-14T15:26:16Z | pt_BR |
| Access date | 2016-07-15T18:40:38Z | |
| Available date | 2016-07-14T15:26:16Z | pt_BR |
| Available date | 2016-07-15T18:40:38Z | |
| Document date | 2013 | |
| Citation | COUTINHO-NETO, Antonio et al. ESI-MS/MS Identification of a Bradykinin-Potentiating Peptide from Amazon Bothrops atrox Snake Venom Using a Hybrid Qq-oaTOF Mass Spectrometer. Toxins, v. 5, p. 327-335, 2013. | eng |
| URI | https://www.arca.fiocruz.br/handle/icict/14947 | |
| Language | eng | pt_BR |
| Publisher | Toxins | eng |
| Rights | open access | pt_BR |
| Title | ESI-MS/MS Identification of a Bradykinin-Potentiating Peptide from Amazon Bothrops atrox Snake Venom Using a Hybrid Qq-oaTOF Mass Spectrometer | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.3390/toxins5020327 | pt_BR |
| Abstract | A bradykinin-potentiating peptide (BPP) from Amazon Bothrops atrox venom with m/z 1384.7386 was identified and characterized by collision induced dissociation (CID) using an ESI-MS/MS spectra obtained in positive ion mode on a hybrid Qq-oaTOF mass spectrometer, Xevo G2 QTof MS (Waters, Manchester, UK). De novo peptide sequence analysis of the CID fragmentation spectra showed the amino acid sequence ZKWPRPGPEIPP, with a pyroglutamic acid and theoretical monoisotopic m/z 1384.7378, which is similar to experimental data, showing a mass accuracy of 0.6 ppm. The peptide is homologous to other BPP from Bothrops moojeni and was named as BPP-BAX12. | eng |
| Affilliation | Fundação Oswaldo Cruz. Fiocruz Rondônia. Center of Biomolecules Study Applied to Health. Porto Velho, RO, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Fiocruz Rondônia. Center of Biomolecules Study Applied to Health. Porto Velho, RO, Brasil. | pt_BR |
| Affilliation | Waters Corporation. MS Applications Development Laboratory. Alphaville, SP, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Fiocruz Rondônia. Center of Biomolecules Study Applied to Health. Porto Velho, RO, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Fiocruz Rondônia. Center of Biomolecules Study Applied to Health. Porto Velho, RO, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Fiocruz Rondônia. Center of Biomolecules Study Applied to Health. Porto Velho, RO, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Fiocruz Rondônia. Center of Biomolecules Study Applied to Health. Porto Velho, RO, Brasil / Federal University of Rondônia. Medicine Department. Porto Velho, RO, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Fiocruz Rondônia. Center of Biomolecules Study Applied to Health. Porto Velho, RO, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Fiocruz Rondônia. Center of Biomolecules Study Applied to Health. Porto Velho, RO, Brasil / Federal University of Rondônia. Medicine Department. Porto Velho, RO, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Fiocruz Rondônia. Center of Biomolecules Study Applied to Health. Porto Velho, RO, Brasil. / Federal University of Rondônia. Medicine Department. Porto Velho, RO, Brasil. | pt_BR |
| Subject | Bioactive peptide | eng |
| Subject | BPP | eng |
| Subject | Pyroglutamic acid | eng |
| Subject | Pyrrolidonecarboxylic acid | eng |
| Subject | Peptide sequencing | eng |
