| Author | Aulicino, Paula C. | |
| Author | Gómez-Carrillo, Manuel | |
| Author | Bello, Gonzalo | |
| Author | Rocco, Carlos | |
| Author | Mangano, Andrea | |
| Author | Carr, Jean | |
| Author | Sen, Luisa | |
| Author | Foley, Brian | |
| Access date | 2016-09-15T11:36:03Z | |
| Available date | 2016-09-15T11:36:03Z | |
| Document date | 2012 | |
| Citation | AULICINO, Paula C. et al. Characterization of full-length HIV-1 CRF17_BF genomes and comparison to the prototype CRF12_BF strains. Infect Genet Evol., v.12, n.2, p.443-447, Mar. 2012. | pt_BR |
| ISSN | 1567-1348 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/15801 | |
| Language | eng | pt_BR |
| Publisher | Elsevier | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | subtipos de HIV-1 | pt_BR |
| Subject in Portuguese | Argentina | pt_BR |
| Subject in Portuguese | Epidemiologia molecular | pt_BR |
| Title | Characterization of full-length HIV-1 CRF17_BF genomes and comparison to the prototype CRF12_BF strains | pt_BR |
| Type | Article | |
| DOI | 10.1016/j.meegid.2012.01.003 | |
| Abstract | The aim of this work is to characterize the full-length intersubtype recombinant structure of the HIV-1 Circulating Recombinant Form CRF17_BF. A single genome of CRF17_BF was originally described in 2001 as being largely similar to CRF12_BF. Since then, more genomes of CRF17_BF have been sequenced but not adequately described in publications. Here we describe CRF17_BF as a genuine CRF, and analyze its recombination pattern based on bootscan analyses, subtype signature patterns, and phylogenetic reconstruction of subtype-delimited segments. We show that CRF17_BF can be distinguished from CRF12_BF in several regions of the genome, including vpu, pol, env and nef. A complete and accurate characterization and description of recombination breakpoints in CRFs is required for a proper surveillance of HIV-1 genotypes, and important for epidemiological purposes. | pt_BR |
| Affilliation | Hospital de Pediatría J. P. Garrahan. Laboratorio de Biología Celular y Retrovirus-CONICET. Buenos Aires, Argentina. | pt_BR |
| Affilliation | Universidade de Buenos Aires. Escola de Medicina. Departamento de Microbiologia. Centro Nacional de Referência em AIDS. Buenos Aires, Argentina. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Hospital de Pediatría J. P. Garrahan. Laboratorio de Biología Celular y Retrovirus-CONICET. Buenos Aires, Argentina. | pt_BR |
| Affilliation | Hospital de Pediatría J. P. Garrahan. Laboratorio de Biología Celular y Retrovirus-CONICET. Buenos Aires, Argentina. | pt_BR |
| Affilliation | University of Maryland. School of Medicine. Institute of Human Virology. Department of Epidemiology and Prevention. Baltimore, MD, USA. | pt_BR |
| Affilliation | Hospital de Pediatría J. P. Garrahan. Laboratorio de Biología Celular y Retrovirus-CONICET. Buenos Aires, Argentina. | pt_BR |
| Affilliation | Los Alamos National Laboratory. Theoretical Biology Group. Los Alamos, USA. | pt_BR |
| Subject | HIV-1 subtypes | pt_BR |
| Subject | Argentina | pt_BR |
| Subject | BF recombinants | pt_BR |
| Subject | HIV diversity | pt_BR |
| Subject | Molecular epidemiology | pt_BR |
| Subject | CRF17_BF | pt_BR |
| e-ISSN | 1567-7257 | |
| Embargo date | 2030-01-01 | |
| xmlui.metadata.dc.subject.ods | 10 Redução das desigualdades | |
