| Author | Bello, Gonzalo | |
| Author | Soares, Marcelo A. | |
| Author | Schrago, Carlos G. | |
| Access date | 2016-09-20T17:12:17Z | |
| Available date | 2016-09-20T17:12:17Z | |
| Document date | 2011 | |
| Citation | BELLO, Gonzalo; SOARES, Marcelo A.; SCHRAGO, Carlos G. The Use of Bioinformatics for Studying HIV Evolutionary and Epidemiological History in South America. AIDS Research and Treatment, v.2011, Article ID 154945, 13p, 2011. | pt_BR |
| ISSN | 2090-1240 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/15873 | |
| Language | eng | pt_BR |
| Publisher | Hindawi Publishing Corporation | pt_BR |
| Rights | open access | |
| Subject in Portuguese | HIV-1 | pt_BR |
| Subject in Portuguese | América do Sul | pt_BR |
| Subject in Portuguese | Bioinformática | pt_BR |
| Subject in Portuguese | História epidemiológica | pt_BR |
| Title | The Use of Bioinformatics for Studying HIV Evolutionary and Epidemiological History in South America | pt_BR |
| Type | Article | |
| DOI | 10.1155/2011/154945 | |
| Abstract | The South American human immunodeficiency virus type 1 (HIV-1) epidemic is driven by several subtypes (B, C, and F1) and circulating and unique recombinant forms derived from those subtypes. Those variants are heterogeneously distributed around the continent in a country-specific manner. Despite some inconsistencies mainly derived from sampling biases and analytical constrains, most of studies carried out in the area agreed in pointing out specificities in the evolutionary dynamics of the circulating HIV-1 lineages. In this paper, we covered the theoretical basis, and the application of bioinformatics methods to reconstruct the HIV spatial-temporal dynamics, unveiling relevant information to understand the origin, geographical dissemination and the current molecular scenario of the HIV epidemic in the continent, particularly in the countries of Southern Cone. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Instituto de Microbiologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Departamento de Genética. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Câncer. Programa de Genética. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Departamento de Genética. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Human immunodeficiency virus type 1 (HIV-1) | pt_BR |
| Subject | South America | pt_BR |
| Subject | Bioinformatics | pt_BR |
| Subject | Epidemiological History | pt_BR |
| e-ISSN | 2090-1259 | |
