| Author | Coelho, Flavio Codeço | |
| Author | Durovni, Betina | |
| Author | Saraceni, Valeria | |
| Author | Lemos, Cristina | |
| Author | Codeco, Claudia Torres | |
| Author | Camargo, Sabrina | |
| Author | Carvalho, Luiz Max de | |
| Author | Bastos, Leonardo | |
| Author | Arduini, Denise | |
| Author | Villela, Daniel A M | |
| Author | Armstrong, Margaret | |
| Access date | 2016-11-30T12:44:38Z | |
| Available date | 2016-11-30T12:44:38Z | |
| Document date | 2016 | |
| Citation | COELHO, Flavio Codeço et al. Higher incidence of Zika in adult women than adult men in Rio de Janeiro suggests a significant contribution of sexual transmission from men to women. International Journal of Infectious Diseases, v.51, p. 128–132, 2016. | pt_BR |
| ISSN | 1201-9712 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/16378 | |
| Language | por | pt_BR |
| Publisher | Elsevier | en |
| Rights | open access | en |
| Title | Higher incidence of Zika in adult women than adult men in Rio de Janeiro suggests a significant contribution of sexual transmission from men to women | pt_BR |
| Type | Article | en |
| DOI | 10.1016/j.ijid.2016.08.023 | pt_BR |
| Abstract | The recent emergence of Zika in Brazil and its association with an increased rate of congenital malformations has raised concerns over its impact on the birth rate in the country. Using data on the incidence of Zika in 2015-2016 and dengue in 2013 and 2015-2016 for the city of Rio de Janeiro (population 6.4 million), a massive increase of Zika in women compared to men was documented. | |
| Abstract | Objectives: The recent emergence of Zika in Brazil and its association with an increased rate of congenital
malformations has raised concerns over its impact on the birth rate in the country. Using data on the
incidence of Zika in 2015–2016 and dengue in 2013 and 2015–2016 for the city of Rio de Janeiro (population 6.4 million), a massive increase of Zika in women compared to men was documented. Methods: The age-adjusted incidence was compared between men and women. A negative binomial Poisson generalized linear model was fitted to the Zika incidence data to determine the significance of sexual transmission statistically.
Results: Even after correcting for the bias due to the systematic testing of pregnant women for Zika, there
were found to be 90% more registered cases per 100 000 women than men in the sexually active age
group (15–65 years); this was not the case for age groups <15 years and >65 years. Assuming that
infected men transmit the disease to women in their semen, but that the converse is not true, some extra
incidence in women is to be expected. An alternate hypothesis would be that women visit doctors more
often than men. To test this, the incidence of dengue fever was compared in men and women in 2015 and
in 2013 (before Zika reached Rio de Janeiro): in both years, women were 30% more likely to be reported
with dengue. Conclusion: Women in the sexually active age group are far more likely to get Zika than men (+90% increase); sexual transmission is the most probable cause. Women in the 15–65 years age group are also 30% more likely to be reported with dengue than men, which is probably due to women being more
careful with their health. | en |
| Affilliation | Fundação Getúlio Vargas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Prefeitura do Rio de Janeiro. Secretaria Municipal de Saúde. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Prefeitura do Rio de Janeiro. Secretaria Municipal de Saúde. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Prefeitura do Rio de Janeiro. Secretaria Municipal de Saúde. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Presidência. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Getúlio Vargas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Presidência. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Getúlio Vargas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Presidência. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil / University of Edinburgh. Institute of Evolutionary Biology, Edinburgh, UK. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Presidência. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Prefeitura do Rio de Janeiro. Secretaria Municipal de Saúde. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Presidência. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Getúlio Vargas. Rio de Janeiro, RJ, Brasil / MINES Paristech. PSL Research University. CERNA Centre for Industrial Economy. Paris, France. | pt_BR |
| Subject | Zika | en |
| Subject | Sexual transmission | en |
| Subject | Dengue | en |
| Subject | Age-adjusted incidence | en |
| DeCS | Zika virus | pt_BR |
| DeCS | Dengue | pt_BR |
