| Author | Grimaldi Jr., Gabriel | |
| Author | Teva, Antonio | |
| Author | Santos, Claudiney B. | |
| Author | Ferreira, Adelson L. | |
| Author | Falqueto, Aloísio | |
| Access date | 2017-04-17T12:57:17Z | |
| Available date | 2017-04-17T12:57:17Z | |
| Document date | 2012 | |
| Citation | GRIMALDI JR., Gabriel; TEVA, Antonio; SANTOS, Claudiney B.; FERREIRA, Adelson L.; FALQUETO, Aloísio. the effect of removing potentially infectious dogs on the numbers of Canine Leishmania infantum infections in an endemic area with high transmission rates. Am. J. Trop. Med. Hyg., San Francisco, CA, v. 86, n. 6, p. 966–971, 2012. | pt_BR |
| ISSN | 0002-9637 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/18460 | |
| Language | eng | pt_BR |
| Publisher | American Society of Tropical Medicine and Hygiene | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Leishmania | pt_BR |
| Subject in Portuguese | Leishmania infantum | pt_BR |
| Subject in Portuguese | Cães | pt_BR |
| Subject in Portuguese | Infecção | pt_BR |
| Title | The effect of removing potentially infectious dogs on the numbers of Canine Leishmania infantum Infections in an endemic area with high transmission rates | pt_BR |
| Type | Article | |
| DOI | 10.4269/ajtmh.2012.12-0040 | pt_BR |
| Abstract | To assess the effect of the rapid removal of potentially infectious dogs on the prevalence and incidence of canine infections, a prospective study was undertaken in an area endemic for Leishmania infantum. We used serological testing based on the rapid DPP rK28 fusion protein chromatographic immunoassay for this dog screening-and-culling
intervention trial. The outcome was evaluated by measuring seropositivity and sero-conversion/-reversion rates for canine infection. Our estimates indicated that concomitant detection and elimination of seropositive dogs with active disease may affect the numbers of canine infections and disease burden temporarily, although it is insufficient as a measure to interrupt the zoonotic L. infantum transmission. However, most of the asymptomatic, seropositive dogs continuously exhibit low levels of antibodies and/or reverted, remaining seronegative thereafter. In the process of waiting for an effective vaccine, one option for canine reservoir control may be to identify these possibly genetically resistant animals and promote their expansion in the population. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório de Patologia e Biointervenção. Salvador, BA, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Leishmaniose. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Espírito Santo. Unidade de Medicina Tropical, Centro de Ciências da Saúde. Vitória, ES, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Espírito Santo. Unidade de Medicina Tropical, Centro de Ciências da Saúde. Vitória, ES, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Espírito Santo. Unidade de Medicina Tropical, Centro de Ciências da Saúde. Vitória, ES, Brasil. | pt_BR |
| Subject | Leishmania | pt_BR |
| Subject | Leishmania infantum | pt_BR |
| Subject | Dogs | pt_BR |
| Subject | Infection | pt_BR |
| Subject | High Transmission Rates | pt_BR |
| DeCS | Leishmania | pt_BR |
| DeCS | Cães | pt_BR |
| DeCS | Infecção | pt_BR |
| DeCS | Leishmania infantum | pt_BR |
