| Author | Meis, Juliana de | |
| Author | Oliveira, Désio Aurélio Farias de | |
| Author | Panzenhagen, Pedro H. Nunes | |
| Author | Maran, Naiara | |
| Author | Villa-Verde, Déa Maria Serra | |
| Author | Morrot, Alexandre | |
| Author | Savino, Wilson | |
| Access date | 2017-04-18T16:48:52Z | |
| Available date | 2017-04-18T16:48:52Z | |
| Document date | 2012 | |
| Citation | MEIS, Juliana de: et al. Thymus Atrophy and Double-Positive Escape Are Common Features in Infectious Diseases. Journal of Parasitology Research, Volume 2012, Article ID 574020, 9p, 2012. | pt_BR |
| ISSN | 2090-0023 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/18501 | |
| Language | eng | pt_BR |
| Publisher | Hindawi Publishing Corporation | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Timo | pt_BR |
| Subject in Portuguese | Trypanosoma cruzi | pt_BR |
| Subject in Portuguese | Infecção | pt_BR |
| Subject in Portuguese | Atrofia do Timo | pt_BR |
| Subject in Portuguese | Linfócitos do timo | pt_BR |
| Title | Thymus atrophy and double-positive escape are common features in infectious diseases | pt_BR |
| Type | Article | |
| DOI | 10.1155/2012/574020 | |
| Abstract | The thymus is a primary lymphoid organ in which bone marrow-derived T-cell precursors undergo differentiation, leading to migration of positively selected thymocytes to the T-cell-dependent areas of secondary lymphoid organs. This organ can undergo atrophy, caused by several endogenous and exogenous factors such as ageing, hormone fluctuations, and infectious agents. This paper will focus on emerging data on the thymic atrophy caused by infectious agents. We present data on the dynamics of thymus lymphocytes during acute Trypanosoma cruzi infection, showing that the resulting thymus atrophy comprises the abnormal release of thymic-derived T cells and may have an impact on host immune response. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Microbiologia. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil / Universidade Federal do Rio de Janeiro. Instituto de Microbiologia. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Subject | Thymus | pt_BR |
| Subject | Thymus Atrophy | pt_BR |
| Subject | Trypanosoma cruzi infection | pt_BR |
| Subject | thymus lymphocytes | pt_BR |
| e-ISSN | 2090-0031 | |
