| Author | Cruz, Helena Medina | |
| Author | Scalioni, Leticia de Paula | |
| Author | Paula, Vanessa Salete de | |
| Author | Miguel, Juliana Custódio | |
| Author | Ó, Kycia Maria Rodrigues do | |
| Author | Milagres, Flavio Augusto Pádua | |
| Author | Cruz, Marcelo Santos | |
| Author | Bastos, Francisco Inácio Pinkusfeld Monteiro | |
| Author | Flores, Priscila Pollo | |
| Author | Leal, Erotildes | |
| Author | Castro, Ana Rita Coimbra Motta | |
| Author | Lewis-Ximenez, Lia Laura | |
| Author | Lampe, Elisabeth | |
| Author | Villar, Livia Melo | |
| Access date | 2017-05-04T13:07:02Z | |
| Available date | 2017-05-04T13:07:02Z | |
| Document date | 2017 | |
| Citation | CRUZ, Helena Medina; et al. Poor sensitivity of rapid tests for the detection of antibodies to the hepatitis B virus: implications for field studies. Mem Inst Oswaldo Cruz, v. 112, n.3, p.209-213, Mar. 2017. | en_US |
| ISSN | 0074-0276 | |
| URI | https://www.arca.fiocruz.br/handle/icict/18741 | |
| Language | eng | en_US |
| Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz | en_US |
| Rights | open access | |
| Subject in Portuguese | Vírus da Hepatite B | en_US |
| Subject in Portuguese | Anticorpos | en_US |
| Subject in Portuguese | Performance | en_US |
| Subject in Portuguese | Testes rápidos | en_US |
| Title | Poor sensitivity of rapid tests for the detection of antibodies to the hepatitis B virus: implications for field studies | en_US |
| Type | Article | |
| DOI | 10.1590/0074-02760160394 | |
| Abstract | Rapid tests (RTs) can be used as an alternative method for the conventional diagnosis of hepatitis B virus (HBV). This study aims to evaluate antibodies to HBsAg (anti-HBs) and antibodies to HBeAg (anti-HBe) RTs under different Brazilian settings. The following three groups were included: GI: viral hepatitis outpatient services; GII: low resource areas; and GIII: crack users and beauticians. Imuno-rápido anti-HBsAg™ and Imuno-rápido anti-HBeAg™ RTs were evaluated and showed specificities greater than 95% in all groups. The sensitivity values to anti-HBs were 50.38%, 51.05% and 46.73% and the sensitivity values to anti-HBe were 76.99%, 10.34% and 11.76% in the GI, GII and GIII groups, respectively. The assays had a low sensitivity and high specificity, which indicated their use for screening in regions endemic for HBV. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Hospital São Lucas. Petrópolis, RJ, Brasil. | en_US |
| Affilliation | Universidade Federal do Tocantins. Faculdade de Medicina. Palmas, TO, Brasil. | en_US |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Psiquiatria. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Comunicação e Informação Científica e Tecnológica em Saúde. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Universidade de Brasília. Brasília, DF, Brasil. | en_US |
| Affilliation | Universidade Federal do Rio de Janeiro. Campus Macaé. Macaé, RJ, Brasil. | en_US |
| Affilliation | Universidade Federal do Mato Grosso do Sul. Departamento de Bioquímica e Farmácia. Campo Grande, MS, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | en_US |
| Subject | hepatitis B virus | en_US |
| Subject | antibodies | en_US |
| Subject | rapid tests | en_US |
| Subject | performance | en_US |
| e-ISSN | 1678-8060 | |
