| Author | Castro, Vagner de | |
| Author | Origa, Andréa Fernanda | |
| Author | Bizzacchi, Joyce Maria Annichino | |
| Author | Soares, Manoel do Carmo Pereira | |
| Author | Menezes, R. C | |
| Author | Gonçalves, Marilda de Souza | |
| Author | Costa, Fernando Ferreira | |
| Author | Arruda, Valder Roberval | |
| Access date | 2017-06-09T16:30:08Z | |
| Available date | 2017-06-09T16:30:08Z | |
| Document date | 1999 | |
| Citation | CASTRO, V. et al. Frequencies of platelet-specific alloantigen systems 1–5 in three distinct ethnic groups in Brazil. European Journal of Immunogenetics, v. 26, p. 355-360, 1999. | pt_BR |
| ISSN | 0960-7420 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/19358 | |
| Description | Marilda de Souza Gonçalves “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. | pt_BR |
| Language | eng | pt_BR |
| Publisher | Blackwell Science | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Plaquetas | pt_BR |
| Subject in Portuguese | Doença Vascular | pt_BR |
| Subject in Portuguese | Grupos etnicos | pt_BR |
| Subject in Portuguese | Alelos | pt_BR |
| Subject in Portuguese | Brasil | pt_BR |
| Title | Frequencies of platelet-specific alloantigen systems 1–5 in three distinct ethnic groups in Brazil | pt_BR |
| Type | Article | pt_BR |
| Abstract | The human platelet antigen (HPA) systems are related to
immune platelet disorders as well as to the development
of occlusive vascular disease. Several distinct biallelic
HPA systems are known, and a heterogeneous distribution
of HPA alleles has been described among distinct
ethnic groups. In this study we genotyped 320 carefully
selected individuals from three distinct ethnic groups in
Brazil (Caucasians, Blacks and Amazonian Indians) for
the HPA-1, -2, -3, -4 and -5 systems. A similar prevalence
for all HPA alleles was found in Brazilians of Caucasian
and Black descent. These data contrast with those
reported for similar ethnic groups in other countries.
Among the Amazonian Indians, no b allele of the HPA-
1, -4 and -5 systems was identified. The data presented
here could be useful in the diagnosis of alloimmune
platelet disease, in genetic counselling and in the development
of screening programmes for HPA-related diseases | pt_BR |
| Affilliation | State University of Campinas. Hematology and Hemotherapy Center. Campinas, SP, Brasil | pt_BR |
| Affilliation | State University of Campinas. Hematology and Hemotherapy Center. Campinas, SP, Brasil | pt_BR |
| Affilliation | State University of Campinas. Hematology and Hemotherapy Center. Campinas, SP, Brasil | pt_BR |
| Affilliation | Evandro Chagas Institute. Belém, PA, Brasil | pt_BR |
| Affilliation | Evandro Chagas Institute. Belém, PA, Brasil | pt_BR |
| Affilliation | Universidade Federal da Bahia. Salvador, BA, Brasil | pt_BR |
| Affilliation | State University of Campinas. Hematology and Hemotherapy Center. Campinas, SP, Brasil | pt_BR |
| Affilliation | State University of Campinas. Hematology and Hemotherapy Center. Campinas, SP, Brasil | pt_BR |
| Subject | Platelet | pt_BR |
| Subject | Occlusive vascular | pt_BR |
| Subject | Ethnic groups | pt_BR |
| Subject | Alleles | pt_BR |
| Subject | Brazil | pt_BR |
| DeCS | Plaquetas | pt_BR |
| DeCS | Doença Vascular | pt_BR |
| DeCS | Grupos etnicos | pt_BR |
| DeCS | Alelos | pt_BR |
| DeCS | Brazil | pt_BR |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
