| Author | Magalhães, Belisa Maria Lopes | |
| Author | Coelho, Leíla Ines Aguiar Raposo Câmara | |
| Author | Maciel, Marcel Gonçalves | |
| Author | Ferreira, João Marcos Benfica Barbosa | |
| Author | Umezawa, Eufrozina Setsu | |
| Author | Coura, José Rodrigues | |
| Author | Guerra, Jorge Augusto de Oliveira | |
| Author | Barbosa, Maria das Graças Vale | |
| Access date | 2017-06-13T16:43:07Z | |
| Available date | 2017-06-13T16:43:07Z | |
| Document date | 2011 | |
| Citation | MAGALHÂES, Belisa Maria Lopes; et al. Serological survey for Chagas disease in the rural areas of Manaus, Coari, and Tefé in the Western Brazilian Amazon. Revista da Sociedade Brasileira de Medicina Tropical, v.44, n.6, p.697-702, Nov-Dez, 2011. | pt_BR |
| ISSN | 0037-8682 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/19376 | |
| Language | eng | pt_BR |
| Publisher | Sociedade Brasileira de Medicina Tropical | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Amazônia Brasileira | pt_BR |
| Subject in Portuguese | Doença de Chagas | pt_BR |
| Subject in Portuguese | Pesquisa Sorológica | pt_BR |
| Title | Serological survey for Chagas disease in the rural areas of Manaus, Coari, and Tefé in the Western Brazilian Amazon | pt_BR |
| Alternative title | Inquérito sorológico para doença de Chagas em áreas rurais de Manaus, Coari e Tefé na Amazônia Ocidental | pt_BR |
| Type | Article | |
| Abstract | Introduction: Deforestation, uncontrolled forest, human population migration from endemic
areas, and the large number of reservoirs and wild vectors naturally infected by Trypanosoma
cruzi promote the endemicity of Chagas disease in the Amazon region. Methods: We
conducted an initial serological survey (ELISA) in a sample of 1,263 persons; 1,095 (86.7%)
were natives of the state of Amazonas, 666 (52.7%) were male, and 948 (75.1%) were over
20 years old. Serum samples that were found to be reactive, indeterminate, or inconclusive by
indirect immunofluorescence (IFI) or positive with low titer by IFA were tested by Western
blot (WB). Serologically confirmed patients (WB) were evaluated in terms of epidemiological,
clinical, ECG, and echocardiography characteristics. Results: Fifteen patients had serologically
confirmed T. cruzi infection, and 12 of them were autochthonous to the state of Amazonas,
for an overall seroprevalence of 1.2% and 0.9% for the state of Amazonas. Five of the 15 cases
were males, and the average age was 47 years old; most were farmers with low education. One
patient who was not autochthonous, having originated from Alagoas, showed right bundle
branch block, bundle branch block, and anterosuperior left ventricular systolic dysfunction
with an ejection fraction of 54%. Conclusions: The results of this study ratify the importance
of monitoring CD cases in Amazonia, particularly in the state of Amazonas. | pt_BR |
| Affilliation | Universidade do Estado do Amazonas. Programa de Pós-graduação em Medicina Tropical. Escola Superior de Ciências da Saúde. Manaus, AM, Brasil. | pt_BR |
| Affilliation | Fundação de Medicina Tropical Heitor Vieira Dourado. Gerência de Entolomogia e Leishmaniose. Manaus, AM, Brasil / Universidade Federal do Amazonas. Faculdade de Farmácia. Manaus, AM, Brasil / Universidade Federal do Amazonas. Faculdade de Medicina. Manaus, AM, Brasil | pt_BR |
| Affilliation | Universidade do Estado do Amazonas. Programa de Pós-graduação em Medicina Tropical. Escola Superior de Ciências da Saúde. Manaus, AM, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Amazonas. Faculdade de Farmácia. Manaus, AM, Brasil / Universidade Federal do Amazonas. Faculdade de Medicina. Manaus, AM, Brasil | pt_BR |
| Affilliation | Instituto de Medicina Tropical de São Paulo. Laboratório de Doenças Parasitárias. São Paulo, SP, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Doenças Parasitárias. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Universidade do Estado do Amazonas. Programa de Pós-graduação em Medicina Tropical. Escola Superior de Ciências da Saúde. Manaus, AM, Brasil./ Fundação de Medicina Tropical Heitor Vieira Dourado. Gerência de Entolomogia e Leishmaniose. Manaus, AM, Brasil. | pt_BR |
| Affilliation | Universidade do Estado do Amazonas. Programa de Pós-graduação em Medicina Tropical. Escola Superior de Ciências da Saúde. Manaus, AM, Brasil./ Fundação de Medicina Tropical Heitor Vieira Dourado. Gerência de Entolomogia e Leishmaniose. Manaus, AM, Brasil / Universidade Nilton Lins. Departamento de Biologia. Manaus, AM, Brasil. | pt_BR |
| Subject | Chagas Disease | pt_BR |
| Subject | Serological Survey | pt_BR |
| Subject | Brazilian Amazon | pt_BR |
| e-ISSN | 1678-9849 | |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
