| Author | Limongi, J. E. | |
| Author | Oliveira, R. C. | |
| Author | Guterres, A. | |
| Author | Costa Neto, S. F. | |
| Author | Fernandes, J. | |
| Author | Vicente, L. H. B. | |
| Author | Coelho, M. G. | |
| Author | Ramos, V. N. | |
| Author | Ferreira, M. S. | |
| Author | Bonvicino, C. R. | |
| Author | D'Andrea, P. S. | |
| Author | Lemos, E. R. S. | |
| Access date | 2017-06-23T18:53:13Z | |
| Available date | 2017-06-23T18:53:13Z | |
| Document date | 2016 | |
| Citation | LIMONGI, J. E. et al. Hantavirus pulmonary syndrome and rodent reservoirs in the savanna-like biome of Brazil’s southeastern region. Epidemiol. Infect., v.144, p.1107-1116, 2016. | pt_BR |
| ISSN | 0950-2688 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/19503 | |
| Language | eng | pt_BR |
| Publisher | Cambridge University Press | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Vírus Araraquara | pt_BR |
| Subject in Portuguese | Síndrome pulmonar de hantavirus | pt_BR |
| Subject in Portuguese | Roedores | pt_BR |
| Subject in Portuguese | Necromys lasiurus | pt_BR |
| Title | Hantavirus pulmonary syndrome and rodent reservoirs in the savanna-like biome of Brazil's southeastern region | pt_BR |
| Type | Article | |
| DOI | 10.1017/S095026881500237X | |
| Abstract | This paper describes the diversity of rodent fauna in an area endemic for hantavirus cardiopulmonary syndrome (HCPS) in Brazil, the population dynamics and the relationship of rodents with hantavirus in the Cerrado (savanna-like) biome. Additionally, an analysis is made of the partial S segment sequences of the hantaviruses obtained from serologically confirmed human HCPS cases and from rodent specimens. Rodents were collected during four campaigns. Human serum samples were collected from suspected cases of HCPS at hospitals in the state of Minas Gerais. The samples antibody-reactive by ELISA were processed by RT-PCR. The PCR product was amplified and sequenced. Hantavirus was detected only in Necromys lasiurus, the wild rodent species most prevalent in the Cerrado biome (min-max: 50-83·7%). All the six human serum samples were hantavirus seropositive and five showed amplified PCR products. The analysis of the nucleotide sequences showed the circulation of a single genotype, the Araraquara hantavirus. The environmental changes that have occurred in the Cerrado biome in recent decades have favoured N. lasiurus in interspecific competition of habitats, thus increasing the risk of contact between humans and rodent species infected with hantavirus. Our data corroborate the definition of N. lasiurus as the main hantavirus reservoir in the Cerrado biome. | pt_BR |
| Affilliation | Universidade Federal de Uberlândia. Instituto de Geografia. Curso de Saúde Ambiental. Uberlândia, MG, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswado Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia e Parasitologia de Mamíferos Silvestres Reservatórios. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Uberlândia. Faculdade de Medicina Veterinária. Laboratório de Ixodologia. Uberlândia, MG, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Uberlândia. Faculdade de Medicina Veterinária. Laboratório de Ixodologia. Uberlândia, MG, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Uberlândia. Faculdade de Medicina. Departamento de Molésticas Infecciosas. Uberlândia, MG, Brasil. | pt_BR |
| Affilliation | Fundação Oswado Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia e Parasitologia de Mamíferos Silvestres Reservatórios. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswado Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia e Parasitologia de Mamíferos Silvestres Reservatórios. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Araraquara virus | pt_BR |
| Subject | hantavirus pulmonary syndrome | pt_BR |
| Subject | Necromys lasiurus | pt_BR |
| Subject | Rodentia | pt_BR |
| e-ISSN | 1469-4409 | |
| Embargo date | 2030-01-01 | |
