| Author | Mares-Guia, Maria Angélica M. M. | |
| Author | Rozental, Tatiana | |
| Author | Guterres, Alexandro | |
| Author | Ferreira, Michelle dos Santos | |
| Author | Botticini, Renato De Gasperis | |
| Author | Terra, Ana Kely Carolina | |
| Author | Marraschi, Sandro | |
| Author | Bochner, Rosany | |
| Author | Lemos, Elba R. S. de | |
| Access date | 2017-06-23T19:16:23Z | |
| Available date | 2017-06-23T19:16:23Z | |
| Document date | 2016 | |
| Citation | MARES-GUIA, Maria Angélica M. M. et al. Molecular Identification of Q Fever in Patients with a Suspected Diagnosis of Dengue in Brazil in 2013–2014. Am. J. Trop. Med. Hyg., v.94, n.5, p.1090–1094, Feb. 2016, | en_US |
| ISSN | 0002-9637 | |
| URI | https://www.arca.fiocruz.br/handle/icict/19504 | |
| Description | Published online feb. 2016. Ssubject to Restrictions below, author can archive publisher's version/PDF
Restrictions: - 12 months embargo | en_US |
| Language | eng | en_US |
| Publisher | American Society of Tropical Medicine and Hygiene | en_US |
| Rights | open access | |
| Subject in Portuguese | Febre Q | en_US |
| Subject in Portuguese | Vírus da dengue | en_US |
| Subject in Portuguese | Identificação molecular | en_US |
| Subject in Portuguese | Brasil | en_US |
| Title | Molecular Identification of Q Fever in Patients with a Suspected Diagnosis of Dengue in Brazil in 2013-2014 | en_US |
| Type | Article | |
| DOI | 10.4269/ajtmh.15-0575 | |
| Abstract | Q fever is an important cause of undifferentiated fever that is rarely recognized or reported in Brazil. The objective of this study was to look for the presence of Coxiella burnetii during a dengue fever outbreak in the municipality of Itaboraí, Rio de Janeiro, Brazil, where this bacterium had previously infected humans and domesticated animals. Blood samples from clinically suspected dengue fever patients were tested by polymerase chain reaction (PCR) for C. burnetii; the DNA was detected in nine (3.3%) of 272 patients. One was coinfected with dengue virus, which was also detected in another 166 (61.3%) patients. The nucleotide sequence of PCR amplification and DNA sequencing of the IS1111 transposase elements in the genome of C. burnetii exhibited 99% identity with the sequence in GenBank. The detection of C. burnetii in patients suspected of dengue fever indicates that awareness and knowledge of Q fever should be strengthened and that this bacterium is present in Brazil. Finally, because a negative molecular result does not completely rule out the diagnosis of Q fever and the serological assay based on seroconversion was not available, the actual number of this zoonosis is likely to be much higher than that reported in this study. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Hospital Municipal Desembargador Leal Junior. Laboratório de Análises Clínicas. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Hospital Municipal Desembargador Leal Junior. Laboratório de Análises Clínicas. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Hospital Municipal Desembargador Leal Junior. Laboratório de Análises Clínicas. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Comunicação e Informação Científica e Tecnológica em Saúde. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hantaviroses e Rickettsioses. Rio de Janeiro, RJ, Brasil. | en_US |
| Subject | Q Fever | en_US |
| Subject | Dengue | en_US |
| Subject | Molecular Identification | en_US |
| Subject | Brazil | en_US |
| e-ISSN | 1476-1645 | |
