| Author | Parente, Thiago E. | |
| Author | Moreira, Daniel A. | |
| Author | Magalhães, Maithê G. P. | |
| Author | Andrade, Paula C. C. de | |
| Author | Furtado, Carolina | |
| Author | Haas, Brian J. | |
| Author | Stegeman, John J. | |
| Author | Hahn, Mark E. | |
| Access date | 2017-07-19T11:39:51Z | |
| Available date | 2017-07-19T11:39:51Z | |
| Document date | 2017 | |
| Citation | PARENTE, Thiago E. et al. The liver transcriptome of suckermouth armoured catfish (Pterygoplichthys anisitsi, Loricariidae): Identification of expansions in defensome gene families. Marine Pollution Bulletin, v.115, n.1-2, p.352–361, 2017. | pt_BR |
| ISSN | 0025-326X | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/20144 | |
| Language | eng | pt_BR |
| Publisher | els | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Peixes-Gato | pt_BR |
| Subject in Portuguese | Receptores nucleares | pt_BR |
| Subject in Portuguese | Transportadores de Cassetes de Ligação de ATP | pt_BR |
| Subject in Portuguese | Sistema Enzimático do Citocromo P-450 | pt_BR |
| Title | The liver transcriptome of suckermouth armoured catfish (Pterygoplichthys anisitsi, Loricariidae): Identification of expansions in defensome gene families | pt_BR |
| Type | Article | |
| DOI | 10.1016/j.marpolbul.2016.12.012 | |
| Abstract | Pterygoplichthys is a genus of related suckermouth armoured catfishes native to South America, which have invaded tropical and subtropical regions worldwide. Physiological features, including an augmented resistance to organic xenobiotics, may have aided their settlement in foreign habitats. The liver transcriptome of Pterygoplichthys anisitsi was sequenced and used to characterize the diversity of mRNAs potentially involved in the responses to natural and anthropogenic chemicals. In total, 66,642 transcripts were assembled. Among the identified defensome genes, cytochromes P450 (CYP) were the most abundant, followed by sulfotransferases (SULT), nuclear receptors (NR) and ATP binding cassette transporters (ABC). A novel expansion in the CYP2Y subfamily was identified, as well as an independent expansion of the CYP2AAs. Two expansions were also observed among SULT1. Thirty-two transcripts were classified into twelve subfamilies of NR, while 21 encoded ABC transporters. The diversity of defensome transcripts sequenced herein could contribute to this species' resistance to organic xenobiotics. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sérgio Arouca. Laboratório de Toxicologia Ambiental. Rio de Janeiro, RJ. Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microorganismos. Rio de Janeiro, RJ, Brasil / Woods Hole Oceonagraphic Instituttion. Woods Hole, MA, USA. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sérgio Arouca. Laboratório de Toxicologia Ambiental. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Instituto Nacional de Câncer. Unidade de Genômica. Rio de Janeiro, RJ, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sérgio Arouca. Laboratório de Toxicologia Ambiental. Rio de Janeiro, RJ. Brasil | pt_BR |
| Affilliation | Instituto Nacional de Câncer. Unidade de Genômica. Rio de Janeiro, RJ, Brasil | pt_BR |
| Affilliation | Broad Institute of Massachusetts Institute of Technology and Harvard. Cambridge, MA 02142, USA. | pt_BR |
| Affilliation | Woods Hole Oceonagraphic Instituttion. Woods Hole, MA, USA. | pt_BR |
| Affilliation | Woods Hole Oceonagraphic Instituttion. Woods Hole, MA, USA. | pt_BR |
| Subject | RNA-Seq | pt_BR |
| Subject | P450 | pt_BR |
| Subject | SULT | pt_BR |
| Subject | ABC transporters | pt_BR |
| Subject | Nuclear receptors | pt_BR |
| Embargo date | 2030-01-01 | |
| xmlui.metadata.dc.subject.ods | 14 Vida na água | |
