| Author | Andrade, Elisa Helena Paz de | |
| Author | Vilela, Ana Paula Pessoa | |
| Author | Rosa, Júlio C. C. | |
| Author | Miranda, Daniela Pádua Jardim de | |
| Author | Ferreira, Paulo César Peregrino | |
| Author | kroon, Erna Geessien | |
| Author | Figueiredo, Leandra Barcelos | |
| Author | Abrahão, Jônatas Santos | |
| Author | Oliveira, Jaquelline Germano de | |
| Author | Zibaoui, Hassan M. | |
| Author | Araújo, Valdelaine Etelvina Miranda de | |
| Access date | 2017-07-25T18:31:20Z | |
| Available date | 2017-07-25T18:31:20Z | |
| Document date | 2016 | |
| Citation | ANDRADE, Elisa Helena Paz et al. Spatial-Temporal Co-Circulation of Dengue Virus 1, 2, 3, and 4 Associated with Coinfection Cases in a Hyperendemic Area of Brazil: A 4-Week Survey. Am J Trop Med Hyg., v. 94, n. 5, p. 1080-4, 2016. | pt_BR |
| ISSN | 0002-9637 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/20402 | |
| Language | eng | pt_BR |
| Publisher | American Society of Tropical Medicine and Hygiene | pt_BR |
| Rights | restricted access | pt_BR |
| Subject in Portuguese | Dengue | pt_BR |
| Title | Spatial-Temporal Co-Circulation of Dengue Virus 1, 2, 3, and 4 Associated with Coinfection Cases in a Hyperendemic Area of Brazil: A 4-Week Survey | pt_BR |
| Type | Article | |
| DOI | 10.4269/ajtmh.15-0892 | |
| Abstract | Dengue is currently regarded as a major public health problem worldwide. In a hyperendemic region during an outbreak, we detected the co-circulation of all Dengue virus (DENV) serotypes including two different genotypes of DENV-3 and DENV-4, and concurrent infections with up to three serotypes were identified in symptomatic patients. A total of 49 acute phase plasma samples from patients clinically suspected of dengue were collected during the 4 weeks of May 2013. DENV-1-4 was detected by reverse transcriptase semi-nested polymerase chain reaction in 33 samples (67.3%), of which 26 DNA fragments were sequenced. Twenty samples (76.9%) were identified with a single DENV serotype and six (23.1%) with more than one serotype. DENV-3 was the predominant serotype of the outbreak. On the basis of phylogenetic analyses, DENV-1 isolates belong to genotype V, DENV-2 to American–Asian genotype, DENV-3 to genotypes I and III, and DENV-4 to genotypes I and II. | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Departamento de Microbiologia. Belo Horizonte, MG. Brazil/Prefeitura Municipal de Contagem. Secretaria de Saúde. Contagem, MG, Brazil | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Departamento de Microbiologia. Belo Horizonte, MG. Brazil | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Departamento de Microbiologia. Belo Horizonte, MG. Brazil | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Departamento de Microbiologia. Belo Horizonte, MG. Brazil | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Departamento de Microbiologia. Belo Horizonte, MG. Brazil | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Laboratório de Vírus. Belo Horizonte, MG, Brasil | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Departamento de Microbiologia. Laboratório de Vírus. Belo Horizonte, MG. Brazil | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Departamento de Microbiologia. Laboratório de Vírus. Belo Horizonte, MG. Brazil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Imunologia Celular e Molecular. Belo Horizonte, MG. Brazil | pt_BR |
| Affilliation | Prefeitura Municipal de Contagem. Secretaria de Saúde. Contagem, MG, Brazil | pt_BR |
| Affilliation | Prefeitura Municipal de Contagem. Secretaria de Saúde. Contagem, MG, Brazil | pt_BR |
| Subject | Dengue | pt_BR |
| Embargo date | 2025-01-01 | |
