| Author | Campos, Renata de Oliveira | |
| Author | Barreto, Iasmin dos Santos | |
| Author | Maia, Lorena Rejane de Jesus | |
| Author | Rebouças, Sara Cristina Lima | |
| Author | Cerqueira, Taíse Lima de Oliveira | |
| Author | Oliveira, Clotilde Assis | |
| Author | Santos, Carlos Antônio de Souza Teles | |
| Author | Mendes, Carlos Maurício Cardeal | |
| Author | Teixeira, Leonardo Sena Gomes | |
| Author | Ramos, Helton Estrela | |
| Access date | 2018-02-07T13:36:39Z | |
| Available date | 2018-02-07T13:36:39Z | |
| Document date | 2015 | |
| Citation | CAMPOS, R. O. et al. Iodine nutritional status in Brazil: a meta-analysis of all studies performed in the country pinpoints to an insufficient evaluation and heterogeneity. Archives of Endocrinology and Metabolism, v. 59, p. 13-22, 2015. | pt_BR |
| ISSN | 2359-3997 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/24747 | |
| Description | Santos, Carlos Antônio de Souza Teles. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. | pt_BR |
| Sponsorship | State of Bahia Research Foundation (Fapesb--PET 0002/2013; Edict 29/2012). | pt_BR |
| Language | eng | pt_BR |
| Publisher | Brazilian Society of Endocrinology and Metabolism | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Iodo | pt_BR |
| Subject in Portuguese | Hipotireoidismo | pt_BR |
| Subject in Portuguese | Deficiência de iodo | pt_BR |
| Subject in Portuguese | Brasil | pt_BR |
| Title | Iodine nutritional status in Brazil: a meta-analysis of all studies performed in the country pinpoints to an insufficient evaluation and heterogeneity | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1590/2359-3997000000004 | |
| Abstract | Iodine deficiency disorder (IDD) is the result of an inadequate dietary intake of iodine, which physiological consequences are endemic goiter and thyroid dysfunction. The objective of this study was to a analyze studies that assessed the status of Brazil's population iodine nutrition and IDD prevalence. Materials and methods: Systematic review using PRISMA statement. Electronic
database: PubMed, Medline, SciELO and Lilacs. Quality of studies: Newcastle-Ottawa Scale. Metaanalysis
was carried out with R Core Team Statistical Software, version 3.1.0 (2014). The summary
measure (WMD) and its confidence interval (CI) of 95% were calculated. The “Funnel plot” graph
assessed publication bias and heterogeneity. Results: Seventeen papers were eligible: pregnant
women (2), school children (9), adults/elderly (4) and preschool children/infants (2). Geographic distribution:
North (1), Northeast (1), Midwest (2), Southeast (13), South (3). Twenty-three thousand two
hundred seventy-two subjects were evaluated between 1997 and 2013 and all have use urinary iodine
(UI) measurement. However, only 7 studies could be included in meta-analysis, all from Southeast region.
The overall prevalence of IDD in school children in southeast region was 15.3% (95% CI, 13-35%),
however this data had an important heterogeneity, expressed by the I² Statistic of 99.5%. Conclusion:
Only few studies have been performed and enrolled populations from south/southeast region of
Brazil. The actual IDD prevalence analysis is complex because it was detected bias due influence of individual
studies and very high heterogeneity. IDD might still be high in some areas but this remained
unknown even after this meta-analysis evaluation. The generation of a national program for analysis
of iodine status in all regions is urgently required. | pt_BR |
| Affilliation | Universidade Federal da Bahia. Instituto de Saúde e Ciências. Departamento de Bioregulação. Salvador, BA, Brasil / Universidade Federal da Bahia. Health & Science Institute. Program in Interactive Processes of Organs and Systems. Salvador, BA, Brasil | pt_BR |
| Affilliation | Universidade Federal da Bahia. Instituto de Saúde e Ciências. Departamento de Bioregulação. Salvador, BA, Brasil | pt_BR |
| Affilliation | Universidade Federal da Bahia. Instituto de Saúde e Ciências. Departamento de Bioregulação. Salvador, BA, Brasil | pt_BR |
| Affilliation | Universidade Federal da Bahia. Instituto de Saúde e Ciências. Departamento de Bioregulação. Salvador, BA, Brasil | pt_BR |
| Affilliation | Universidade Federal da Bahia. Instituto de Saúde e Ciências. Departamento de Bioregulação. Salvador, BA, Brasil | pt_BR |
| Affilliation | Universidade Federal do Recôncavo da Bahia. Centro de Saúde e Ciências. Santo Antonio de Jesus, BA, Brasil | pt_BR |
| Affilliation | Universidade Estadual de Feira de Santana. Departamento de Estatística. Feira de Santana, BA, Brasil | pt_BR |
| Affilliation | Universidade Federal da Bahia. Health & Science Institute. Program in Interactive Processes of Organs and Systems. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Saúde e Ciências. Departamento de Biofunção. Salvador, BA, Brasil | pt_BR |
| Affilliation | Universidade Federal da Bahia. Instituto de Química. Salvador, BA, Brasil | pt_BR |
| Affilliation | Universidade Federal da Bahia. Instituto de Saúde e Ciências. Departamento de Bioregulação. Salvador, BA, Brasil / Universidade Federal da Bahia. Health & Science Institute. Program in Interactive Processes of Organs and Systems. Salvador, BA, Brasil | pt_BR |
| Subject | Iodine | pt_BR |
| Subject | Hypothyroidism | pt_BR |
| Subject | Iodine deficiency | pt_BR |
| Subject | Brazil | pt_BR |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
