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https://www.arca.fiocruz.br/handle/icict/24937
RAPID AND ACCURATE INTERPRETATION OF DENGUE DIAGNOSTICS IN THE CONTEXT OF DENGUE VACCINATION IMPLEMENTATION: VIEWPOINTS AND GUIDELINES ISSUED FROM AN EXPERTS GROUP CONSULTATION
Author
Affilliation
Global Disease Detection Regional Center. Centers for Disease Control. Nairobi, Kenya.
Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Virologia Molecular. Curitiba, PR, Brasil.
Pasteur Institute of Ho Chi Minh City. Arbovirus Laboratory, Ho Chi Minh City, Vietnam.
Mahidol University. Center for Vaccine Development. Bangkok, Thailand.
Instituto Pasteur, Paris, France.
Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Virologia Molecular. Curitiba, PR, Brasil.
Pasteur Institute of Ho Chi Minh City. Arbovirus Laboratory, Ho Chi Minh City, Vietnam.
Mahidol University. Center for Vaccine Development. Bangkok, Thailand.
Instituto Pasteur, Paris, France.
Abstract
This paper conclud that assess the overall benefits of vaccination in high burden countries for dengue, long-term surveillance will require a robust, affordable, and user-friendly diagnostic algorithm to detect suspected dengue cases. After that Since a large variability in the results of the diagnostics may occur between different kits and laboratories worldwide, future phase IV studies of CYD-TDV vaccine effectiveness should use the proposed combined diagnostic testing with the same validated and standardized kits/ protocols and international guidelines when designing sentinel sites to ensure quality assurance and to enhance data sharing and comparability across regions.
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