| Author | Oliveira, Priscilla Alexandrino de | |
| Author | Oliveira, Joanna Reis Santos | |
| Author | Dorval, Maria Elizabeth Cavalheiros | |
| Author | Costa, Francisco das Chagas Brandão da | |
| Author | Pereira, Gracy Regina Oliveira Leite | |
| Author | Cunha, Rivaldo Venâncio da | |
| Author | Paniago, Anamaria Mello Miranda | |
| Author | Cruz, Alda Maria da | |
| Access date | 2018-03-08T17:02:52Z | |
| Available date | 2018-03-08T17:02:52Z | |
| Document date | 2010 | |
| Citation | OLIVEIRA, Priscilla Alexandrino de; et al. HIV/AIDS-associated visceral leishmaniasis in patients from an endemic area in central-west Brazil. Mem Inst Oswaldo Cruz,v.105, n.5, p.692-697, Aug. 2010. | pt_BR |
| ISSN | 0074-0276 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/25202 | |
| Language | eng | pt_BR |
| Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz | pt_BR |
| Rights | open access | |
| Subject in Portuguese | HIV | pt_BR |
| Subject in Portuguese | Aids | pt_BR |
| Subject in Portuguese | Infecções oportunistas | pt_BR |
| Subject in Portuguese | Brasil | pt_BR |
| Subject in Portuguese | Leishmaniose visceral | pt_BR |
| Subject in Portuguese | usuários de drogas intravenosas | pt_BR |
| Subject in Portuguese | recorrência | pt_BR |
| Title | HIV/AIDS-associated visceral leishmaniasis in patients from an endemic area in central-west Brazil | pt_BR |
| Type | Article | |
| Abstract | An increase in morbidity associated with visceral leishmaniasis (VL) in human immunodeficiency virus (HIV)/AIDS patients has been described in Africa and the Mediterranean. Despite the high endemicity of VL and HIV-1/AIDS in Brazil, this association has not been thoroughly investigated. Our aim was to evaluate the epidemiologic and clinical characteristics of VL-HIV-1/AIDS cases from central-west [Mato Grosso do Sul (MS)] Brazil. Medical records of 23 VL-HIV-1/AIDS patients were reviewed. Patients were predominantly adult males (87%) and 34.8% of the patients were intravenous drug users (IVDU). Leishmaniasis was the first opportunistic infection in 60% of the HIV-1 patients. Fever occurred in all patients, although splenomegaly and hepatomegaly were absent in 21.7% of the cases. CD4+ T-cell counts were below 200 cells/mm3 in 80% of the cases and the counts did not increase after clinical remission despite antiretroviral therapy. The first drug chosen to treat the cases was antimonial, but the therapeutic regimen was altered to amphotericin B in 12 of 17 cases due to side effects. Relapses were reported in 56.5% of the patients. IVDU may constitute an important risk factor for the transmission of both diseases in MS. VL-HIV-1/AIDS patients in MS share similar clinical characteristics as those from other endemic regions worldwide. Thus, these findings are critical for improving the surveillance of VL-HIV/AIDS patients. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ. Brasil / Universidade Federal do Mato Grosso do Sul. Hospital Universitário. Campo Grande, MS, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Universidade Federal do Mato Grosso do Sul. Departamento de Patologia. Campo Grande, MS, Brasil | pt_BR |
| Affilliation | Prefeitura Municipal de Campo Grande. Centro de Doenças Infecciosas e Parasitárias. Campo Grande, MS, Brasil | pt_BR |
| Affilliation | Universidade Federal do Mato Grosso do Sul. Hospital Universitário. Campo Grande, MS, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Mato Grosso do Sul. Departamento de Clínica Médica. Campo Grande, MS, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Mato Grosso do Sul. Departamento de Clínica Médica. Campo Grande, MS, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Subject | HIV/AIDS | pt_BR |
| Subject | opportunistic infections | pt_BR |
| Subject | Brazil | pt_BR |
| Subject | visceral leishmaniasis | pt_BR |
| Subject | intravenous drug users | pt_BR |
| Subject | recurrence | pt_BR |
| e-ISSN | 1678-8060 | |
