| Author | Souza, Marcus Vinícius Dias | |
| Author | Santos, Renan Martins dos | |
| Author | Siqueira Filho, Ezequias Pessoa de | |
| Author | Marçal, Pedro Henrique Ferreira | |
| Access date | 2018-03-19T17:21:23Z | |
| Available date | 2018-03-19T17:21:23Z | |
| Document date | 2017 | |
| Citation | SOUZA, Marcus Vinícius Dias et al.. Antibiofilm activity of cashew juice pulp against Staphylococcus aureus, high performance liquid chromatography/diode array detection and gas chromatography-mass spectrometry analyses, and interference on antimicrobial drugs. J Food Drug Anal. , v. 25, n. 3, p. 589-596, 2017 | pt_BR |
| ISSN | 1021-9498 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/25400 | |
| Language | eng | pt_BR |
| Publisher | Elsevier Taiwan | pt_BR |
| Rights | restricted access | pt_BR |
| Subject in Portuguese | antibioticos | pt_BR |
| Subject in Portuguese | Staphylococcus aureus | pt_BR |
| Title | Antibiofilm activity of cashew juice pulp against Staphylococcus aureus, high performance liquid chromatography/diode array detection and gas chromatography-mass spectrometry analyses, and interference on antimicrobial drugs | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1016/j.jfda.2016.07.009 | |
| Abstract | The epidemiology of Staphylococcus aureus infections has evolved in recent years, as this species is a major Gram-positive pathogen associated with healthcare services. The antimicrobial resistance of this species raises an urgent need for new treatment strategies. Fruits play important nutritional and economic roles in society, but their biological and pharmacological features are poorly explored when compared to nonedible parts of plants such as barks and leaves. In this study, we show that the cashew apple juice [cashew juice pulp (CJP)] extract is active against the planktonic cells of S. aureus strains, and for the first time, we show that CJP is also active against S. aureus biofilms. High performance liquid chromatography and gas chromatography-mass spectrometry analyses were conducted to prospect for polyphenols and free carbohydrates, respectively. Cashew apple juice, which is rich in nutrients, is widely consumed in Brazil; therefore, the quality attributes of CJPs were investigated. Samples were evaluated for pH, total titratable acidity, vitamin C levels, and total soluble solids. We also detected an antagonistic interference of CJP when it was combined with different antimicrobial drugs. | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Instituto de Ciências Biologicas, Belo Horizonte, MG, Brazil/Grupo de Pesquisas de Integração Medicamentosas. Belo Horizonte, MG, Brazil. | pt_BR |
| Affilliation | Grupo de Pesquisas de Integração Medicamentosas. Belo Horizonte, MG, Brazil/Universidade Federal de Minas Gerais. Faculdade de Farmacia. Belo Horizonte, MG, Brazil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brazil. | pt_BR |
| Affilliation | Grupo de Pesquisas de Integração Medicamentosas. Belo Horizonte, MG, Brazil/Universidade Federal de Juiz de Fora. Juiz de Fora, MG, Brazil/Universidade do Vale do Rio Doce. Governador Valadares, MG, Brazil. | pt_BR |
| Subject | Antimicrobial | pt_BR |
| Subject | Staphylococcus aureus | pt_BR |
| Subject | cashew | pt_BR |
| Subject | pulp | pt_BR |
| Embargo date | 2025-01-01 | |
