| Author | Gómez, M. M. | |
| Author | Volotão, E. M. | |
| Author | Mendonça, M. C. Lima de | |
| Author | Tort, L. F. L. | |
| Author | Silva, M. F. M. da | |
| Author | Leite, J. P. G. | |
| Access date | 2018-03-20T14:12:24Z | |
| Available date | 2018-03-20T14:12:24Z | |
| Document date | 2010 | |
| Citation | GÓMEZ, M. M. et al. Detection of Uncommon Rotavirus A Strains P[8]G8 and P[4]G8 in the City of Rio de Janeiro, 2002. Journal of Medical Virology, v. 82, p.1272–1276, 2010. | pt_BR |
| ISSN | 0146-6615 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/25421 | |
| Language | eng | pt_BR |
| Publisher | Wiley | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Rotavirus A | pt_BR |
| Subject in Portuguese | Gastroenterite | pt_BR |
| Subject in Portuguese | Genótipo G8 | pt_BR |
| Subject in Portuguese | evolução do vírus | pt_BR |
| Subject in Portuguese | Rio de Janeiro | pt_BR |
| Title | Detection of uncommon rotavirus A strains P[8]G8 and P[4]G8 in the city of Rio de Janeiro, 2002 | pt_BR |
| Type | Article | |
| DOI | 10.1002/jmv.21769 | |
| Abstract | Group A rotaviruses (RV-A) are the major cause of gastroenteritis in infants and young children around the world. Each year RV-A causes approximately 11 million episodes of severe diarrhea, with an estimated of 611,000 deaths. Epidemiologic surveys have identified P[8]G1, P[4]G2, P[8]G3, P[8]G4, and P[8]G9 as the most common global genotypes associated with diarrhea in children up to 5-year old. Surveillance studies and documentation of RV-A G and P genotypes is necessary for a comprehensive evaluation of the evolution of new strains, and assessing the capability of vaccines to provide heterotypic protection. It is known that reassortments are the driving force for genetic diversity through sudden changes in RV-A genome. In this study, we identified two unusual P/G combinations, P[8]G8 and P[4]G8, occurring in Rio de Janeiro during 2002. Results obtained in this study suggest that P[8]G8 RV-A strain originated from a reassortment event that occurred between RV-A P[4]G8 and P[8]G9 strains circulating in Rio de Janeiro in the same year. G8 strains identified in this study, as well as G8 strains detected in Recife by Montenegro et al. [Montenegro et al. (2007) J Med Virol 79: 335-340], showed a close genetic relationship with strains from Africa, where this genotype have become prevalent. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Subject | rotavirus A | pt_BR |
| Subject | gastroenteritis | pt_BR |
| Subject | genotype G8 | pt_BR |
| Subject | reassortment | pt_BR |
| Subject | virus evolution | pt_BR |
| Subject | Rio de Janeiro | pt_BR |
| e-ISSN | 1096-9071 | |
| Embargo date | 2030-01-01 | |
