| Author | Grybchuk, Danyil | |
| Author | Kostygov, Alexei Y. | |
| Author | Macedo, Diego H. | |
| Author | d`Avila-Levy, Claudia M. | |
| Author | Yurchenko, Vyacheslav | |
| Access date | 2018-05-03T13:27:08Z | |
| Available date | 2018-05-03T13:27:08Z | |
| Document date | 2018 | |
| Citation | GRYBCHUK, Danyil; et al. RNA viruses in trypanosomatid parasites: a historical overview. Mem Inst Oswaldo Cruz, v.113, n.4, e170487, 2018. | pt_BR |
| ISSN | 0074-0276 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/26232 | |
| Language | eng | pt_BR |
| Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Tripanosomatídeos | pt_BR |
| Subject in Portuguese | Leishmaniavirus | pt_BR |
| Subject in Portuguese | Vírus de RNA | pt_BR |
| Title | RNA viruses in trypanosomatid parasites: a historical overview | pt_BR |
| Type | Article | |
| DOI | 10.1590/0074-02760170487 | |
| Abstract | Viruses of trypanosomatids are now being extensively studied because of their diversity and the roles they play in flagellates' biology. Among the most prominent examples are leishmaniaviruses implicated in pathogenesis of Leishmania parasites. Here, we present a historical overview of this field, starting with early reports of virus-like particles on electron microphotographs, and culminating in detailed molecular descriptions of viruses obtained using modern next generation sequencing-based techniques. Because of their diversity, different life cycle strategies and host specificity, we believe that trypanosomatids are a fertile ground for further explorations to better understand viral evolution, routes of transitions, and molecular mechanisms of adaptation to different hosts. | pt_BR |
| Affilliation | University of Ostrava. Faculty of Science. Life Science Research Centre. Ostrava, Czech Republic. | pt_BR |
| Affilliation | University of Ostrava. Faculty of Science. Life Science Research Centre. Ostrava, Czech Republic. | pt_BR |
| Affilliation | University of Ostrava. Faculty of Science. Life Science Research Centre. Ostrava, Czech Republic. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Estudos Integrados em Protozoologia. Coleção de Protozoários, Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | University of Ostrava. Faculty of Science. Life Science Research Centre. Ostrava, Czech Republic. | pt_BR |
| Subject | trypanosomatidae | pt_BR |
| Subject | RNA viruses | pt_BR |
| Subject | leishmaniavirus | pt_BR |
| e-ISSN | 1678-8060 | |
